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DnbNor Health Care Summit 19 September, 2006 Important news expected shortly
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2 Content Positioned to: – Become the first player with Marketing Authorization in all EU/EEA-countries for glucosamine – Become the first vertically integrated pharmaceutical glucosamine player – Become one of the leading glucosamine players globally, building on our strong partners
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3 Content Market Product Company Milestones
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4 Treating a widespread disease Osteoarthritis, the most widespread form of arthritis – 50 % of people above 65 Traditional medication (pain killers / NSAIDs) may have severe side effects Glucosamine is a a strong alternative – Naturally occurring substance – Favourable safety profile – Relieves pain and improves function – Classified as a medicine in several European countries – Recommended by EULAR* Market Arthritis: A major cause of disability *European League against Rheumatism
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5 An attractive market Global retail value of arthritis drugs NOK ~150-200 billion. Expected strong growth in osteoarthritis (OA) market – Fast growing number and share of people above 60 – Overweight represents an increasing problem Glucosamine market more than NOK 10 billion of which rapidly growing pharma market accounts for NOK >1.5 billion Glucosamine market growth 10-15% Market Source: Reuters Business Insights, IMS, Harvard Medical School, Navamedic data and analysis
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6 Current EU/EEA regulatory status (2006) Prescription medicine Prescription/Over-The Counter (OTC) OTC/Nutra Prescription medicine/ Nutra Nutra/unknown Market
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7 Content Market Product Company Milestones
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8 Glucomed® has substantial advantages 1.HCl easier to administer than sulphate 2.Does not contain NaCl* 3.Quality Glucomed® has substantial advantages over competing glucosamine products *A large share of OA patients also have high blood pressure (hypertension) Product
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9 Content Market Product Company Milestones
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10 Chitin powder Glucosamine powder Positioned to become a leading player Shrimp shells Glucomed ® Company Building unique glucosamine value chain Access to scarce raw material Proprietary low-cost glucosamine production technology Strong marketing and distribution network: 10 partners in 14 countries
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11 Marketing Authorization and Marketing and Distribution agreements, EU/EEA Company Marketing and distribution agreement Glucomed launched in market Marketing Authorization Marketing Authorization and Marketing and distribution agreement In addition: Marketing and distribution agreement in 3 countries outside this region
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12 Going to market Company Where prescription (RX) – Marketing towards and visiting with doctors Where non-prescription (OTC) – Advertising towards patients Where “OTX” – Combination Strong partners: – E.g. Merck, Meda, Gerolymatos – Negotiations with strong potential partners in several countries
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13 Content Market Product Company Milestones
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14 Key milestones Milestones Q2 2007 ->Launch of finished product in markets where MA and Marketing and distribution agreement Q4 2006 ->Further Marketing and distribution agreements Q1 2007Marketing Authorization (MA) in EU/EEA-countries Q1 2007Ratification of conclusion in the EU-commission 18-21 September or 16-19 October Conclusion in EU/EEA product approval process Regulatory Sales and marketing:
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15 Key milestones Milestones Chitin factory in productionQ1 2007 Production with novel glucosamine producion method 2008 Production
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16 Content Summary: – Important milestones in short time – Short time-to-market – Become the first vertically integrated pharmaceutical glucosamin player – Become the first player with Marketing Authorization in all EU/EEA-countries – Become one of the leading glucosamine players globally, building on our strong partners
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