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Published byYAR GUL Modified over 7 years ago
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Ions channels definition of ion channels: A protein that acts as a pore in a cell membrane and permits the selective passage of ions (such as potassium ions, sodium ions, and calcium ions),
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Basic types of ions channels: Leakage Ion channels: which are always open responsible for the resting membrane potential. Gated channels: which open/close in response to a stimulus.
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Classification of gated channels: ligand-gated channels: Ion channels that open/close in response to a chemical messenger binding to the channel. voltage-gated channel: Channels that open/close in response to a change in membrane potential. mechanically gated channels: Open/close in response to a mechanical force on the membrane.
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Models of gating Discrete models : change in one region. Generalized change: general structure change. blocking particle: particle block the channel.
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ligand-gated channels:
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Mechanically gated channel:
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Ions channel diseases:
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