1. Free Powerpoint Templates Page 1 Free Powerpoint Templates Enzyme Target & Activator & Inhibitor Screening Service —Profacgen

2. Free Powerpoint Templates Page 2 Profacgen offers a comprehensive list of high- throughput screening services to specifically and efficiently identify potential enzyme substrates, activators and inhibitors.

3. Free Powerpoint Templates Page 3 Enzymes participate in numerous physiological activities including signal transduction, cell surface recognition and protein modification. To determine possible targets of an enzyme, Profacgen has developed a highly efficient screening system to select candidate substrates, inhibitors or activators by detection of fluorescence, chemo-luminescence or isotopic signal. Generally, the candidate molecules can be selected or synthesized and then immobilized on a solid surface. Detection is performed after incubation with the target enzyme according to the specific experimental design.

4. Free Powerpoint Templates Page 4 Profacgen provides enzyme target screening service for kinase, phosphatase, protease, methyltransferase, glycosyltransferase, acetyltransferase and so on. You can profile your target enzyme against thousands of substrate compounds or proteins, or study various types of protein modifications including phosphorylation, methylation, ubiquitination, SUMOylation, NEDDylation, and nitrosylation. Profacgen offers thousands of substrates from sources including human, rat, mouse, chicken and cow etc.enzyme target screening

5. Free Powerpoint Templates Page 5 Profacgen also provides activator or enzyme inhibitor screening service by adding candidate compounds together with target enzyme into the substrate. The effect of candidate compounds on the kinetics of the given enzymatic reaction can be quantified by the determination of EC50 or IC50 compared to control groups.enzyme inhibitor screening

6. Free Powerpoint Templates Page 6 Our advantages: Short turn-around time High efficiency Optimized experimental scheme Consistent results Customized service Combinatorial libraries available to fine-tune substrate sequence

7. Free Powerpoint Templates Page 7 Contact ProfacgenProfacgen Address: 45-1 Ramsey Road Shirley, NY 11967, USA Website: https://www.profacgen.com/https://www.profacgen.com/