1. High School Presentation
Jeans for Genes Day
High School Presentation

2. What is Jeans for Genes Day?
Section: one
What is Jeans for Genes Day?

3. What is Jeans for Genes Day?
Jeans for Genes Day raises much needed funds for Children’s Medical Research Institute (CMRI).
It’s easy and fun to get involved:
Simply swap your uniform for a pair of jeans and make a gold coin donation
Hold a fundraising event, such as a bake sale or sporting challenge

4. What does CMRI do?
Children’s Medical Research Institute conducts the ‘basic’ research that allows us to understand the fundamental causes of a range of disorders, such as cancer and epilepsy.
This crucial foundation is needed if we are to find ways to treat or prevent these diseases.
We are also dedicated to going beyond basic research, by translating the discoveries made in the laboratory into new treatments for patients through our gene therapy and drug discovery programs.

5. GENETICS: why we are the way we are
There are lots of different things that make you ‘you’ and many are determined by your genes….

6. We all begin as 1 cell

7. Bodies are made of Cells

8. Cells have a Nucleus The nucleus contains Chromosomes
Chromosomes are made of DNA

9. How DNA is packaged in chromosomes:

10. 2.5 m
One cell has 2.5m of DNA!!!
1.96 m
1.78 m
1.64 m
1.63 m
1.53 m

11. Humans have 46 chromosomes (23 pairs)
female
male
sperm =
egg =
X , Y
X , X

12. DNA is needed for Information Transfer

13. 23 chromosomes from the egg and 23 from the sperm combine to make a human

14. To do this, cells need to divide…

15. …and DNA needs to replicate – this can lead to mistakes (or mutations) in genes
G-C
A-T

16. One small mistake can cause a genetic disease
Ginger Pudding
200 gms flour
200gms sugar
2 eggs
125 gms butter
1 tspn ginger
Ginger Pudding
200 gms flour
200gms sugar
2 eggs
125 gms butter
1 tspn finger
A rare mutation gave Jacqui metatropic dysplasia. This disease interfered with her bone growth, so she has severe curvature of the spine, pigeon chest and problems with her joints that will affect her the rest of her life.

17. You can help CMRI find treatments for genetic diseases
You can help CMRI find treatments for genetic diseases. Your donation makes a BIG difference!

18. Thanks for participating in Jeans for Genes Day!!
You are helping to create a healthier, brighter future for children everywhere