1. Characteristics of Health Activation Solutions
Health Activation (patient engagement, population health, personalized medicine, shared accountability, etc.)
Characteristics of Health Activation Solutions
Dramatically high levels of patient engagement and patient satisfaction
Measurable and significant improvements in patient compliance to protocols
Measurable and significant improvements in clinical outcomes
Substantial increase in case management patient management ratios
Measurable and significant reduction in in-person clinical visits (including readmissions) while improving clinical outcomes

2. Type 2 Diabetes Prevention - Omada
Health Activation – Actual Results - Various Healthcare Systems (1 of 6)
Type 2 Diabetes Prevention - Omada
Initial diabetes prevention program (DPP) enrolled more than 2,000 participants over the age of 65. Contrary to the expectations of many, seniors enrolled in the program have been easily able to integrate the technology elements of a digital diabetes prevention program into their daily routines. Six months after starting the program, 84% of participants, with an average age of 69, remained engaged in the program, and lost an average of 7.8% of their body weight. According to the authors of the original DPP trial, this amount of weight loss in participants 60 or older lowered risk of developing diabetes by 71% over three years.
75% of the people who met their first weight-loss goal kept that weight off for three years. In comparison, only 5% of people who lose weight on traditional diets do the same.
Research shows that if you lose just 5% of your weight, your risk of developing type-2 diabetes drops by 58%. Lose 10% or more, and it drops by 85%.
To date, over 30,000 people have participated in the Omada program with similar (though lower) results. Additionally, health plans and employers are only charged for those participants who succeed in measurably lowering their risk for type II diabetes by achieving and maintaining a 5% weight loss from baseline.
Is the “initial diabete4s prevention program” referenced in red text, Omada’s initial trial that they published?
4th bullet – would change to in measurably…..achieving a 5% weight loss from baseline.

3. Diabetes – Twine Health
Health Activation – Actual Results - Various Healthcare Systems (2 of 6)
Diabetes – Twine Health
Average 3.2 drop in HbA1c in 3 months for patients starting basal insulin (typical drop is 0.5 to 1.0 in 1 year)
Diabetes Treatment Satisfaction Questionnaire demonstrated significant experience improvements
Average cost savings per patient estimated to be between $3,000 and $4,000
Hypertension – Twine Health
Average 26mmHg drop in blood pressure in 3 months (typical drop is 6mmHg in a year)
100% of intervention subjects achieved target blood pressure < 140/90 in 3 months
Primary care visits and associated utilization reduced by more than 50% and case load capacity increased by ~3x
Congestive Heart Failure – Sensely
95% of all eligible participants enrolled and used the service continuously
77% of participants compliant with discharge instructions
Growing pilot now has over 80 participants with 4% readmissions compared to current baseline 30 day readmission rate of 16%
Demonstrated cost savings of over 75%
100% members provided very positive feedback

4. Remote Patient Monitoring – Vivify Health (illustrative results)
Health Activation – Actual Results - Various Healthcare Systems (3 of 6)
Remote Patient Monitoring – Vivify Health (illustrative results)
Readmissions
: Reduced readmission from ~20% to 9.1%
: Reduced readmissions from 9.1% to 5.1%
Reduced average admissions from 1.25 to 0.49 per patient
Readmissions reduced by over 50%, from >17% to <5%
Engagement and Satisfaction
Over 95% patient adoption and 98% patient satisfaction
Patient satisfaction exceeding 90%
Healthcare Visits / Length of Stay
Reduced nurse visits by 3.6 per episode
89% reduction in inpatient visits
70% reduction in emergency department visits
Home health LOS reduced from 82 to 48 days
Costs
Cost savings of over $8,500 per patient (n=199)
ROI, including staff, was $3.19 for every $1.00 invested
Reduced average inpatient cost from $16,647 to $6,430

5. Medication adherence, complex patients – CareCentra
Health Activation – Actual Results - Various Healthcare Systems (4 of 6)
COPD – Senscio
100% of patients feel more in command of their health
More than 87% adherence to care plan and 92% medication adherence
More than 90% of exacerbations detected and treated at home (3-7 days earlier than usual). No hospitalizations due to missed exacerbations.
More than 70% reduction in hospitalizations for severe COPD patients
Medication adherence, complex patients – CareCentra
More than 82% Patient Engagement Rate
Over 73% adherence rate
Patients who had a cardio event (heart attack, revascularization, or stroke) – 6 month follow up by IM – 0%
Net recommender score - 9 month follow-up – 100%

6. Empowering Patients at Scale – HealthLoop (illustrative results)
Health Activation – Actual Results - Various Healthcare Systems (5 of 6)
Empowering Patients at Scale – HealthLoop (illustrative results)
Activation, Engagement, and Loyalty
600,000+ patient interactions per month
150+ care pathways across all high volume medical episodes
81% activation rate (% of patients who create an account)
76% engagement rate (% of check-ins completed)
91% of patients ‘Extremely Likely’ to Recommend
2/3 of those patients click through to write reviews on 3rd party review sites (Healthgrades, Vitals, Google, etc.)
Cost Reduction and Efficiency
85% of patients report being able to avoid an office visit or phone call
Care managers report being able to increase the number of patients they can serve by 2x-5x
74% PRO capture at 1 year timepoint with no additional work from staff
Select Customer Results and Peer Reviewed Studies
MD Anderson: 45% increase in comprehension of patient education and instructions (n=2,226)
Cleveland Clinic: 24% reduction in readmissions (n=1,820)
National payer study (pending publication) showing unequivocally that HealthLoop improves quality and lowers cost (n=9,000)
Patient Reported Utilization vs. National Benchmarks
n=90,000+
30% reduction in readmissions
58% increase in discharge-to-home
32% reduction in DVT incidence

7. Parkinson Disease – Wellpepper
Health Activation – Actual Results - Various Healthcare Systems (6 of 6)
Parkinson Disease – Wellpepper
9% improvement in mobility (6-minute walk test) in digital intervention vs control group 12% decline
100% patients would recommend program
85% adherence over 1-year period
Falls Prevention – Wellpepper
Lowest adherence group, twice as likely to fall
Highest adherence group, 3 times less likely to fall
Knee Replacement – Wellpepper
24% improvement in patients with comprehensive care plan versus outcome survey only at one year
All Care Plan Results – Wellpepper
Patient Satisfaction 90%
Over 70% engagement across all patient populations, higher adherence in over 50 populations
At least 20% reduction in unnecessary follow up visits
Identified predictors of greater readmission risk among ambulatory orthopedic surgery patients