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Copyright © 2015 by the American Osteopathic Association.
From: Highlights From the American Diabetes Association's 2017 Standards of Medical Care in Diabetes for Osteopathic Physicians J Am Osteopath Assoc. 2017;117(7): doi: /jaoa Figure Legend: Antihyperglycemic therapy in type 2 diabetes: general recommendations. The order in the chart was determined by historical availability and the route of administration, with injectables to the right; it is not meant to denote any specific preference. Potential sequences of antihyperglycemic therapy for patients with type 2 diabetes are displayed, with the usual transition moving vertically from top to bottom (although horizontal movement within therapy stages is also possible, depending on the circumstances). *See Inzucchi et al19 for description of efficacy categorization. §Usually a basal insulin (neutral protamine Hagedorn, glargine, detemir, degludec). Reprinted from Figure 8.1 in the Standards of Medical Care in Diabetes— Adapted with permission from Inzucchi et al.19 Abbreviations: A1C, hemoglobin A1c; DPP-4-i, dipeptidyl peptidase-4 inhibitor; fxs, fractures; GI, gastrointestinal; GLP-1-RA, glucagon-like peptide-1 receptor agonist; GU, genitourinary; HF, heart failure; Hypo, hypoglycemia; SGLT2-i, sodium-glucose cotransporter-2 inhibitor; SU, sulfonylurea; TZD, thiazolidinedione. Date of download: 9/22/2017 Copyright © 2015 by the American Osteopathic Association. All rights reserved.
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