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CVD prevention/ Tiina Laatikainen

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1 CVD prevention/ Tiina Laatikainen
5th International Seminar on the Public Health Aspects of Noncommunicable Diseases Lausanne, 5-9 September 2011 Finland’s experience in implementing NCD prevention Dr. Tiina Laatikainen, Director Department of Chronic Disease Prevention 13/10/2017 CVD prevention/ Tiina Laatikainen

2 Public health development in Finland after the World War II
Before the War Mainly Infectious Diseases Long, heavy war and difficult post war years The country was very poor In the 1950’s and 60’s Rapid increase in the CVD and other NCD rates Public health response mainly building hospitals and health services

3 In the 1970’s Statistics showed very bad public health situation
CHD mortality rates among men highest in the world Short life expectancy Increasing public discussion General opinion related CHD to stress, ageing and genetics It was earlier also referred to as “Disease of the Executives” Cardiologists were aware that there are numerous “Statistical Associations”

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5 Start of the North Karelia project
North Karelia was part of the Seven Countries Study since 1955 Public attention to the high CVD mortality and to the statistics showing that the province of North Karelia was in the worst situation Petition by the representatives of people in North Karelia for national assistance to cope with the problem (January 1971) Delegation led by the Governor to Helsinki, the petition was handed to the Prime Minister and other decision makers Involvement of Finnish experts and WHO

6 5

7 North Karelia Project Principles for Defining the Intermediate Objectives
• Due to the chronic nature of CVD, the potential for the control of the problem lies in primary prevention • The risk factors were chosen on the basis of best available knowledge: previous studies - collective international recommendations - epidemiological situation in North Karelia • Chosen risk factors: - smoking - elevated serum cholesterol (diet) - elevated blood pressure

8 Serum cholesterol distribution in Finland and Japan in 1970’s
Frequency % mmol/l

9 Main Principles of the North Karelia Project
Prevention is the only sustainable public health approach Risk factors identified by prospective studies, closely linked with certain behaviours - deeply enrooted in the community Community based preventive programme 1 Target: the community (not individuals) 2 Intervention: through community structures (not external intervention) Emphasis on community organization, general community changes

10 CLINICAL INTERVENTION
RISK FACTORS PUBLIC HEALTH INTERVENTION

11 25 % 5 % 70 % Theoretical presentation of the difference between
People with low risk factor level People with average risk factor level People with clinically high risk factor level Individual risk of CHD Distribution of people according to risk factor level Theoretical presentation of the difference between individual risk and the proportional attributable risk

12 Constraints Suspicions from the scientific community of cardiologists
Medical knowledge on prevention questionable, community prevention new concept North Karelia socially deprived area, poor and with many social problems (unemployment, migration, shortage of doctors etc) War and post war years: Great poverty, after that increase in consumption Dairy farming main agriculture: Butter and animal fat culturally highly valued Strong commercial pressures (“FAT WAR”), supported by political pressures Raising the funding (intervention and evaluation research) To maintain interest and funding over decades

13 Advantages Magnitude of problem, concern of people
Relatively homogenous population, traditions of community action Trust in experts and in public action Good information system Good collaboration with people Good leadership

14 Age-adjusted mortality rates of coronary heart disease in North Karelia and the whole of Finland among males aged years from to 2002 700 start of the North Karelia Project 600 extension of the Project nationally 500 North Karelia 400 300 - 82 % All Finland Mortality per population 200 - 75% 100 Year 69 72 75 78 81 84 87 90 93 96 99 2002

15 North Karelia Project Practical intervention
Emphasis on persuasion, practical skills, social & environmental support for change Research team & local project office with comprehensive community involvement Main areas: 1. Media activities (materials, mass media, campaigns) 2. Preventive services (primary health care etc.) 3. Training of professional and other workers 4. Environmental changes (smoke-free areas, supermarkets, food industry etc.) 5. Monitoring and feed-back

16 ANTISMOKING LEGISLATION IN FINLAND IN 1977:
Prohibition of all forms of advertising Restrictions in smoking in public places Health warnings etc. 1/2% level of tobacco tax for antismoking activities Prohibition of sale to under 16 years old ANTISMOKING LEGISLATION IN FINLAND IN 1995, 2000 AND 2007: Worksite smoking policy Sales to persons under 18 years of age prohibited Restaurant, bar smoking policy

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18 Smoking initiation by birth cohort
Daily smoking Smoking initiation by birth cohort % % 60 100 90 50 80 Men Men 70 40 60 30 50 40 20 30 Women Women 20 10 10 1960 1970 1997 1999 2001 2003 2005 1916–20 1921–25 1926–30 1931–35 1936–40 1941–45 1946–50 1951–55 1956–60 1961–65 1966–70 1971–75 1976–80 78-79 83-85 89-90 93-94 19-34 35-49 50-64 25-49 19-34 35-49 50-64 25-49 Helakorpi S et al. J Epidemiol Community Health 2004

19 Smoking control programmes
Voluntary restrictions of smoking in public places Mass media Voluntary restrictions in advertising Use of opinion leaders Training of health care personnel Cessation services in health centres

20 Smoking control programmes
Worksite programmes School programmes TV programmes Radio programmes Quit and Win Competition Smoke Free Class Competition Quit and Win - Do Not Start and Win for Young People

21 A comprehensive television smoking cessation programme in Finland
Voluntary smokers in TV studio tried to stop smoking 6 sessions + 2 follow-up sessions Intensified field activity in North Karelia saw at least 4 sessions attempted to quit quitted remained non-smokers

22 Smoking in men (30–59 y) % North Karelia project evaluation and FINMONICA and the National FINRISK Studies

23 NGO’s role Heart Association Martta (house wife’s) association

24 Active co-operation since 1972
North Karelia Project Co-operation with the Martta (housewifes’) organization Active co-operation since 1972 Several hundred clubs and many thousand members Promotion of health cooking = dietary habits Many special campaigns, notably: - Parties for longlife - Evenings of happy heart

25 Use of lay opinion leaders to promote health innovations in community
Innovation-diffusion theory Training seminars in municipalities Discuss health issues in normal life 805 persons participated Recruitment by local people and Heart Association Evaluation in 1982: 399 (50%) still active

26 Discussions with target groups
Very often (%) Occasionally(%) Family 43 41 Neighbors 18 60 Work 16 31 Relatives 20 48 Friends 46 NGO meetings 13 28 Shopkeepers 8 27 Media 15

27 North Karelia Project Cholesterol programme
SPECIAL INTENSIFIED PROGRAM The program was based especially on the following: - New consensus recommendations - New reference values (< 5 mmol = “normal”) - Fingertip determination method - Interest of food industry - Finnish rapeseed oil MAIN COMPONENTS - Population-wide cholesterol measurements - Dietary counseling - Mass media and many campaigns (incl. Village competition) - Collaboration with industry and supermarkets

28 Village competition to lower cholesterol
villages, population villages, population Village committees organized 2 months competition Baseline and follow-up cholesterol measurement Best village won 2000 €

29 Cholesterol changes in 1991 competition
Village Baseline % Change 1 5.9 -10.8 2 5.8 -9.2 3 -8.9 4 -6.8 5 6.0 -4.0 6 5.7 -2.3 7 +1.4 Mean

30 Cholesterol change in 1997 competition
Baseline End Change Change% N 6.19 5.59 -0.60 -9.0 16

31 Change (%) in cholesterol by number of dietary changes

32 Change (%) in cholesterol value by village activity

33 Fat used for cooking at home in Finland in 1978-2006
Health Behaviour among the Finnish Adult Population 1978–2006

34 Fat intake Recommendations EN% Year The FINDIET Study

35 Serum cholesterol in men aged 30-59 years
mmol/L

36 Cholesterol distribution in North Karelia in 1972 and 2007, men
4 6 8 10 12 mmol/l

37 North Karelia Project Berry project
Aim to increase the consumption of eastern Finnish berries Rationale: 1) Berries are healthy 2) Enhances switch from dairy farming First Berry Project Second Berry Project Methods: various co-operative and innovative interventions

38 Fruits And Vegetables – Supermarkets

39 Changes in Finnish food habits
Year

40 Salt intake in Finland 1977-2007
g/day The FINDIET Study

41 Systolic blood pressure in men (30–59 y)
mmHg North Karelia project evaluation and FINMONICA and the National FINRISK Studies

42 Decline in CHD mortality in men aged 35-64
North Karelia All Finland per

43 Observed and Predicted Decline in CHD mortality
35-64 year old men Vartiainen E et al.

44 Finland Has Shown Prevention of major chronic diseases is possible and pays off Population based prevention is the only cost effective and sustainable public health approach to chronic disease control Prevention calls for simple changes in some lifestyles (individual, family, community, national and global level action) Influencing lifestyles is a key issue Many results of prevention occur surprisingly quickly (CVD, diabetes) and also at relatively late age Comprehensive action, broad collaboration with dedicated leadership and strong government policy support are crucial

45 Why success in North Karelia
Appropriate epidemiological and behavioural framework Restricted, well defined targets Good monitoring of immediate targets (Behaviours, process) Flexible intervention Emphasis in changing environment and social norms Working closely with the community Positive feedback, work with media International collaboration, support from WHO Close interaction with national health policy, integration with National Public Health Institute Long term, dedicated leadership

46 Training seminar on NCD prevention
Helsinki, Finland and in North Karelia 12-16 March, 2012 11-15 March, 2013

47 New textbook on North Karelia project
Pekka Puska, Erkki Vartiainen, Tiina Laatikainen, Pekka Jousilahti, Meri Paavola (eds.) The North Karelia project: from North Karelia to national action Also available in Russian

48 Working intersectorally
Work sites Education Food industry Taxation Working intersectorally Business Media Agriculture Legislation Third sector Research Health services

49 POPULATION PUBLIC POLICY PRIVATE SECTOR HEALTH PROGRAMME

50 Major Elements of Finnish National Action 1.
Research & international research collaboration Health services (especially primary health care) North Karelia Project, other demonstration programmes Health Promotion Programmes (coalitions, NGO’s, collaboration with media etc.) Schools, educational institutions

51 Major Elements of Finnish National Action 2.
Industry, business - collaboration Policy decisions, intersectoral collaboration, legislation Monitoring system: health behaviours, risk factors, nutrition International collaboration

52 Prevention and management of cardiovascular disease
Action Plan for Promoting Finnish Heart Health

53 DPS-F study Diabetes by treatment group during the total follow-up period 50 Log-rank test: p=0.0001 Intervention ceased Control Hazard ratio=0.57 (95% CI ) 40 30 Cumulative incidence of T2D, % 20 Intervention 10 1 2 3 4 5 6 7 8 Follow-up time, years Lindström et. al. Lancet 2006:368;

54 } 15.7% } 11.2% Total*: 41.8% 33.2% Background
Disturbances in glucose metabolism in Finns aged y. FIN-D2D survey 2004 (n=2896) Men Women Diagnosed type diabetes 7.4% 4.3% Screen-detected type 2 diabetes 8.3% 6.9% Impaired glucose tolerance % % Impaired fasting glucose 9.3% 4.8% } 15.7% Total*: % 33.2% } 11.2% * Age-adjusted Suom Lääkäril 2006;61:

55 Development Programme for the Prevention and Care of Diabetes in Finland: DEHKO 2000-2010
Finnish Diabetes Association as initiator and coordinator Preparation of the programme: Approval at a large concensus meeting January 2000 Implementation: First official assessment March 2003

56 Development Programme for the Prevention and Care of Diabetes in Finland: DEHKO 2000-2010
3) Support for Selfcare Education and counselling Rehabilitation Self Support groups Co-operation of associations and professionals Influence at community level 1) Prevention of Type 2 Diabetes The Programme for the prevention of type 2 diabetes in Finland, The Implementation of the prevention programme: Dehko 2D Project (FIN-D2D) 2) Improving the Quality of Diabetes Care The care organization The care chains Quality criteria and the follow-up system of patients Basic and higher education of personnel Non-medical and medical treatment

57 Early diagnosis and treatment strategy
Programme for the Prevention of Type 2 Diabetes in Finland Three strategies: Population strategy High risk strategy Early diagnosis and treatment strategy Population-based strategy / health promotion and more effective lifestyle counselling, prevention of overweight and obesity High risk strategy /prevention or postponing diabetes in those at risk Early diagnosis and treatment strategy / prevention of complications in those diagnosed having diabetes

58 Asthma Programme Focus: (1) inflammation, (2) early intervention, (3) guided self-management, and (4) networking Haahtela T, et al. Thorax 2006 National Allergy Programme – time to act and change the course Finn Med J 2008,Suppl 14:1-22; Allergy 2008;63: ; Allergy 2008;63: , Editorial; Allergy 2009;64: In association with the WHO GARD Programme = Global Alliance against Respiratory Diseases Focus: (1) children, young people, (2) from treatment to prevention, (3) tolerance, (4) diagnostic quality, and (5) early intervention to control severe allergies Ministry of Health; National Public Health Institute; NGOs: Allergy & Asthma Federation, Finnish Lung Health Association, Finnish Pulmonary Association HELI 58

59 Key messages of the Allergy Programme
► Endorse health, not allergy ► Strenghten tolerance ► Adopt a new attitude to allergy. Avoid allergens only if mandatory ► Recognize and treat severe allergies early. Prevent exacerbations ► Improve indoor air quality. Stop smoking ■ Haahtela T, von Hertzen L, Mäkelä M, Hannuksela M, The Allergy Programme Group. Finnish Allergy Programme – time to act and change the course. Allergy 2008 ■ Bousquet J, et al. In Allergy, ”A new day has begun”. Allergy 2008, Editorial 59

60 Allergy Programme Goals 2008-2018
► Prevent allergies. – Prevalences of asthma, allergic rhinitis and atopic dermatitis reduce by 20 %. ► Increase tolerance to allergens in the population. – Avoidance diets to foods decrease by 50 %. ► Improve allergy diagnostics. – All patients are tested in a quality certified allergy-testing centre. ► Reduce work related allergies. – Their numbers reduce by 50 %. ► Use resources to treat severe allergies and reduce exacerbations. – ”Good Allergy Care” is employed in the whole country and asthma exacerbations are reduced by 40 %. ► Reduce costs caused by allergies. – Costs reduce by 20 %. ■ Haahtela T, von Hertzen L, Mäkelä M, Hannuksela M, The Allergy Programme Group. Finnish Allergy Programme – time to act and change the course. Allergy 2008 ■ Bousquet J, et al. In Allergy, ”A new day has begun”. Allergy 2008, Editorial 60

61 Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability OBJECTIVE:
To reduce cognitive impairment in an at risk population through a 2-year multi-domain life-style intervention including: Nutritional guidance Strength training and aerobic exercise Cognitive training, increased social activity Intensive monitoring and management of metabolic and vascular risk factors: hypertension, dyslipidemia, obesity, impaired glucose tolerance 13/10/2017

62 Thank you!

63 Health in All Policies – The Finnish Initiative

64 What is Health in All Policies (HiAP) approach?
Horizontal, complementary policy related strategy The core of HiAP is to examine determinants of health -> are mainly controlled by policies of sectors other than health Addresses policies in the context of policy-making at all levels of governance (global, European, national, regional and local levels) The ultimate aim of HiAP is to improve evidence informed policy-making Health in all policies is closely related to other terms with similar agenda, such as healthy public policies and intersectoral action for health Ståhl et al. (eds). Health in All Policies – Prospects and potentials, 2006

65 Focusing on policies Key concern: policies
The broad economic, social, environmental and cultural health determinants are the bridge between policies and health outcomes For example, alcohol policy (tax) influences the price of alcohol that has an effect on alcohol consumption that (alcohol abuse) in turn has an effect on harms, both health and social Less concerned with single programmes and projects alcohol policy tax on alcohol alcohol consumption health and social harms

66 Broad determinants of health
Social, economic, structural, environmental, cultural Present everywhere in the society Often beyond the control of individuals Same determinants are linked with many major public health problems (nutrition, physical activity, tobacco, alcohol, psychosocial situation, stress) Mostly a responsibility of other government sectors Impossible to target effectively through sectorial health policies alone

67 Intersectoral mechanisms/tools for implementing HiAP
Formal consultations on e.g. legislation Horizontal public health committees Ad hoc committees on specific initiatives Cross-sectorial programmes Public health reporting (with co-operation of other sectors) Formal communication between sectors (e.g. bilateral meetings of Permanent Secretaries) Informal contacts at desk level EU co-ordination Health impact assessment Stahl T (2009) Is health recognized in the EU's policy process? An analysis of the European Commission's impact assessments. The European Journal of Public Health 2009; doi: /eurpub/ckp082


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