1. Acute Pyelonephritis
姜岱山

2. Introduction
Last summer holiday one of my friends told me that she was ill. And she had been on a drip for 7 days. What’s wrong with her? She told me she got acute pyelonephritis.
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3. Main Contents 1. What is APN 2. Etiology and pathogenesis 3. Features
1. What is APN
2. Etiology and pathogenesis
3. Features
4. Complications
5. Clinical
6. Prognosis
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4. What is acute pyelonephritis
APN is a common suppurative inflammation of kidney and the renal pelvis.
APN is caused by bacterial infection, principally E-coil.
APN is an important manifestation of urinary tract infection.
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5. Etiology and pathogenesis
Infection
①hematogenous spread
②ascending infection
Urinary tract obstruction
APN
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6. Suppurative inflammation
Features
APN
Gross patterns
discrete, yellowish, raised abscesses are grossly apparent on the renal surface
Histological
tubular necrosis, and neutrophilic casts, and abscesses formation
patchy
interstitial
Suppurative inflammation
Features
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7. Histological
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8. macrograph
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9. Acute necrotizing paplillitis Perinephric abscesses
Complications
Acute pyelonephritis
Three complications
Acute necrotizing paplillitis
Perinephric abscesses
pyonephrosis
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10. pyonephrosis
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11. Clinical 1
The onset is usually sudden, with pain at costovertebral angle. 2
Systemic evidence of infection such as fever and malaise. 3
Frequency, urgency, urine pain.
Pyuria, bacteriuria, albuminuria, cylindruria, hematuria
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12. chronic pyelonephritis
Prognosis
recovery(most)
active treatment
treatment is delayed.
chronic pyelonephritis
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13. Thank You !