1. Screening Diagnostic Tests for PE
Type of Screening
Tests
General evaluation
MRI, EEG, CMP, CBC, ophthalmologic exam, audiology
Autoimmune disorder
ESR, ANA, complement levels
Autonomic disorder
Histamine skin test, sweat testing
Endocrinopathy
TSH/T4, ACTH, cortisol
Genetic disorder
SNP microarray, MECP2 testing
Infection
CSF cell count, glucose, protein, CSF bacterial/viral cultures, CSF HIV/HSV PCR, CSF fungal antigens, CSF prion proteins, CSF viral antibodies
Intoxication
Lead, urine toxicology
Metabolic disorder
SAA, lactate, pyruvate, ammonia, carnitine, ACP, cholesterol/lipid panel, VLCFA, lysosomal enzyme analysis, lymphocyte vacuolization, UOA, porphyrins, CSF lactate/AA/NT metabolites
Neoplastic disorder
CSF cytologic analysis, paraneoplastic antibodies
Nutritional disorder
Niacin, thiamine, pyridoxine, cobalamin, Vit D, homocysteine, methylmalonic acid