1. IMMUNOHISTOCHEMISTRY
technique which allows to achieve a histological picture able to reveal elements exclusively found in a cell or tissue characterizing the function

2. EMPLOY OF IMMUNOHISTOCHEMISTRY
hormonal receptors
neoplastic cells
proliferating cells
oncoproteins

3. IMMUNOHISTOCHEMICAL DETECTION OF H. PYLORI
ADVANTAGE
not required demonstration of biochemical features to support histology
HANDICAP
high cost: not employed in the clinical practice

4. BrdU (Cahill) and PCNA (Ierardi) LI IN NORMAL STOMACH AND HP GASTRITIS (1994)
(%)

5. BrdU (Cahill) and PCNA (Ierardi) LI IN THE UPPER FOVEOLAR THIRD
(%)
Controls
HP gastritis

6. H. pylori and gastric carcinogenesis
H. pylori and gastric carcinogenesis. Metanalysis of p 53 mutations (Tsuji et al, 1997)

7. immature cells in upper pit
decreased neutral mucins