1. ISRAEL

2. (Click on the graphs under each topic) Diagnostic Substitution
ISRAEL
(Click on the graphs under each topic)
AD Rate
AD Changepoints
Vaccines
MMR
Varicella
N/A
Polio
Hep A
N/A
Diagnostic Substitution
Paternal Age
Thimerosal
N/A
N/A
N/A

3. Data
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4. per 10,000 Birthyear all Jews only rate M F
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per 10,000
Birthyear
all
Jews only
rate M F
1986
9.2
1987
9.1
1988
10.7
1989
10.3
1990
10.4
1991
10.1
1992
11.8
1993
13.4
7.2949
1994
24.031
1995
13.3
1996
14.7
1997
17.4
1998
16.8
1999
2000
16.6
2001 19
2002
21.8
2003
22.1
2004
2005
15.6
2006
3.3
3.7529

5. ASD Changepoint
Birthyears 1981 – 2005,
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6. MEASLES, MUMPS, RUBELLA, VARICELLA
12/1988
MMR II
Combined measles, mumps and rubella with the RA 27/3 strain
Merck
>=12 months
Replaced the single antigen measles vaccine
12 months-6 years
Second dose
1994
2000
Varilrix
Varicella virus vaccine, live
GSK
Approved
1988
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7. History of Polio vaccine used in Israel
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History of Polio vaccine used in Israel
1955
IPV – Salk
  the Central Virology Laboratory of the Ministry of Health
 1,3,30 days
4-6 months
Licensed
1957
Program intiation
1961
M1OPV (monovalent type 1)
 0-3 years
Introduced
1962
M1+M2+M3 OPV
0-3 years
Trivalent OPV
0-1 year
1982
eIPV* + OPV
15 months
*Seed viruses were inoculated in cell cultures derived from either secondary or tertiary subcultures of pathogen-free monkey kidney cells or in Vero African green monkey kidney cell lines