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Use of hyperbaric oxygen therapy and PEGylated carboxyhemoglobin bovine in a Jehovah’s Witness with life-threatening anemia following postpartum hemorrhage K. Thenuwara, J. Thomas, M. Ibsen, U. Ituk, K. Choi, E. Nickel, M.J. Goodheart International Journal of Obstetric Anesthesia Volume 29, Pages (February 2017) DOI: /j.ijoa Copyright © 2016 Elsevier Ltd Terms and Conditions
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Fig. 1 Time line of patient’s hemoglobin. POD: postoperative day; Hb: hemoglobin International Journal of Obstetric Anesthesia , 73-80DOI: ( /j.ijoa ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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Fig. 2 Diagramatic representation of the three functional units of Sanguinate™, and their properties. Hb: hemoglobin; P50: partial pressure in blood when hemglobin is 50% saturated; PEG:polyethylene glycol; NO nitric oxide International Journal of Obstetric Anesthesia , 73-80DOI: ( /j.ijoa ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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Fig. 3 Process for obtaining investigational medication in USA via emergency expanded access of a new investigational agent for a single patient use application. Emergency use of an investigational new drug (eIND) outside of clinical trials to treat patients with serious disease for which there are no other therapeutic options. FDA: Food & Drug Administration (responsible for regulating the use of prescription medications and biologicals); IRB: Institutional Review Board (oversees the safe and ethical conduct of research to ensure the well-being of research participants) International Journal of Obstetric Anesthesia , 73-80DOI: ( /j.ijoa ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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