1. Brain tumor

2. WHO Histologic Classification of CNS tumors:
Neuroepithelial Tumors
Astrocytic tumors
Oligodemdroglial tumors
Ependymal tumors
Mixed gliomas
Choroid plexus tumors
Neurologic tumors
Pineal parenchymal tumors
Embryonal tumors
Tumors of cranial/spinal nerves
Mesenchymal tumors, benign
Mesenchymal tumors, malignant
Uncertain histogenesis
Hemopoietic neoplasms
Cysts/tumorlike lesions
Sellar tumors

3. Prognostic Factors: for malignant astrocytomas
Age
Tumor type
Performance status
Extent of surgery

4. Principles of Treatment:
Surgery: initial treatment
Radiotherapy
Chemotherapy
Combine treatment

5. Estimated Survival: 5 years (%)
Astrocytoma
Grade I (cerebellar) Grade I (all sites) 50-60
Grade II Grade III
Grade IV 0-10
Medulloblastoma
Ependymoma
Oligodendroglioma
Brain stem
3rd ventricle+midbrain 25-35
Pinealoma

6. Roles of Radiotherapy in Brain Tumor
Incomplete surgery
Deep seated tumor: midbrain, pons
Radiosensitive tumor: medulloblastoma
Pituitary adenoma
Palliation: metastatic lesions

7. Roles of Whole Cerebrospinal Axis Irradiation:
Medulloblastoma
Ependymoma: esp. poorly differentiated type
Malignant glioma of posterior fossa
Pinealoma
Choroid plexus papilloma
Reticulum cell sarcoma of the brian

8. Complications and Late Effects of Radiation:
Acute reaction
Brian edema
Early delayed reaction
Necrotizing leukoencephalopathy
Somnolence Syndrome
Late delayed reaction
Cerebral Necrosis
Optic nerve injury