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Immunology of infection, cancer and inflammation

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1 Immunology of infection, cancer and inflammation
A year in the Centre for Innate Immunity and Infectious Diseases Find our projects online: Search by Research Group Head: Paul Hertzog, Brendan Jenkins, Ashley Mansell, Richard Ferrero, Michael Gantier, Phil Bardin Contact our Research Group Heads Professor Paul Hertzog: Professor Brendan Jenkins: Professor Phil Bardin: Associate Professor Richard Ferrero: Associate Professor Ashley Mansell: Dr Michael Gantier: Studying with us as a research student: To work with our researchers, follow the enrolment procedures and fulfil the requirements for the Monash University degrees of the Bachelor of Medical Science (Honours), Bachelor of Biomedical Sciences (Honours) or Bachelor of Sciences (Honours). Several of our research students are enrolled through other universities: talk to us about how this works. Many of our best Honours students stay on to complete PhDs. About Hudson Institute of Medical Research Our research is conducted in the Centre for Innate Immunity and Infectious Diseases at the Hudson Institute of Medical Research. We are located at the Monash Health Translation Precinct, at Wright St in Clayton. Follow us: facebook.com/hudson.org.au linkedin.com/company/hudson-institute-of-medical-research 40 RESEARCH PUBLICATIONS 5 PHD AND HONOURS GRADUATES 19 STUDENTS 36 STAFF 23 DISEASES IMPACTED BY OUR RESEARCH 6 STUDENTS WITH MEDICAL TRAINING Student research Honours and PhD students at the Centre for Innate Immunity and Infectious Diseases at Hudson Institute of Medical Research are trained by Australia’s leading researchers. Students are taught the molecular, cellular and systems biology of the innate immune response as it relates to infectious, inflammatory and neoplastic disease. Our students: attend national and international conferences collaborate with leading researchers undertake an extensive training program regularly win prestigious prizes and awards have opportunities to network publish their research develop technical, communication and presentation skills participate in an active and supportive social club To become a research student at Hudson Institute, contact our Research Group Heads by . Our research has impact on the following diseases: Infection (HIV, Helicobacter, influenza) Cancer (gastric, pancreatic, breast, ovarian) Respiratory disease (asthma & COPD) Gastritis, lupus, septic shock The methods and technologies you will use will underpin the future of preventing, diagnosing and treating disease.

2 What we research Professor Paul Hertzog Dr Michael Gantier
Research Group Head Regulation of Interferon and Innate Signalling Dr Michael Gantier Research Group Head Nucleic Acids and Innate Immunity Associate Professor Ashley Mansell Research Group Head Pattern Recognition Receptors and Inflammation The immune response is important in every disease you’ll study as a scientist or doctor A successful early, innate immune response can resolve infectious diseases and eliminate cancer. A poorly regulated immune response causes chronic inflammatory diseases, with multi-organ impact. We: are world-leaders in research on the innate, or first, immune response perform high quality discovery research using the latest technologies translate our research into preventions, diagnostics and treatments publish in the world's top impact journals Our students are first authors on scientific papers in prestigious journals In 2016, students were first authors on 75 of Hudson Institute's 333 research publications. Some examples from our Centre are: William Berry et al., Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors. Int J Cancer. 2017; 140(10): Martin MacDonald et al., Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease. Lancet Respir Med. 2016; 4(2): Ka Yee Fung et al., Interferon-ε protects the female reproductive tract from viral and bacterial infection. Science. 2013; 339(6123): Our students win prestigious prizes and awards Winner Faculty of Medicine, Nursing and Health Sciences ‘3 Minute Thesis’ Competition – Zoe Marks Travel scholarship from the US National Institute of Allergy and Infectious Disease (NIAID) – Jesse Balic Travel scholarship from the Australian Thoracic Society – Mr Sultan Alhayyani Travel grant from the Science Mobilisation Program of the Embassy of France in Australia – Kimberley D’Costa Winner, PhD Student Prize, Victorian Infection and Immunity Network Young Investigator Symposium – Charlotte Nejad Associate Professor Richard Ferrero Research Group Head Gastrointestinal Infection and Inflammation Professor Philip Bardin Research Group Head Respiratory and Lung Professor Brendan Jenkins Research Group Head Cancer and Immune Signalling Inflammation Sepsis Arthritis Systemic lupus erythematosus Gastrointestinal Gastritis Inflammatory bowel disease Cancer (stomach adenocarcinoma and lymphoma) Women’s health Female reproductive tract infections, cancers and inflammatory diseases Infections HIV Zika virus Influenza Chlamydia Helicobacter pylori Herpes simplex virus Human metapneumovirus Respiratory syncytial virus Cancer Breast Endometrial Lung Ovarian Pancreatic Respiratory Asthma Chronic obstructive pulmonary disease What we research For more information about our student projects in these research areas, consult your handbook or find our projects online.


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