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Endometriosis: A Woman’s Struggle
Nicole Li| Professor Jim Dixon | Biological Research 2017
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What is endometriosis? Displaced endometrial tissue causes Scar tissue
Adhesions Cysts (endometriomas)
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Symptoms “Killer” cramps Pain with bowel movements, urination, etc
Fatigue Constipation Bloating and nausea Infertility Higher risk of ovarian cancer and endometriosis-associated adenocarcinoma
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Current Treatment & (Limited) Diagnosis Methods
Hormone therapy Danazol Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists Surgery Conservative Hysterectomy Pelvic exams- not possible to feel small areas of endometriosis, unless they've caused a cyst to form Ultrasounds- cysts only Laparoscopy- assumes that endometriotic lesions will always be visible when in fact endometriosis can exist microscopically and still cause pain
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Some Little Problems Not everyone can tolerate something. Nothing is effective for everyone. Not everything is available to everyone. Not everything is what it seems.
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SynBio Approaches Disrupted Hormone Sensing Unique miRNA Profiles
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References
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