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Obstetrical emergencies
Nancy E Fay MD FACOG Division of Reproductive Medicine
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Obstetrical Hemorrhage
Blood volume expands by 40% RBC’s increases by 30% = hemodilution Fibrinogen is double the non-pregnant level Uterine blood flow at term > cc/minute 15% of cardiac output Blood loss for vaginal delivery <500 cc Blood loss for c-section <1,000 cc
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First trimester bleeding
Light bleeding: Implantation Ectopic Polyp or cervical irritation Heavy Threatened AB Heavy bleeding: Inevitable or incomplete AB
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Categories of hemorrhage
Class I Loss of 15% of blood volume No change in clinical status BP, RR and HR unchanged Class II Loss of 15-35% blood volume Tachycardic Tachypneic 20-24 Cool, pale and clammy
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Categories of hemorrhage
Class III 30-40% of blood volume Altered mental status Hypotensive, HR >120 Class IV >40% of blood volume Altered mental status or minimal responsiveness Hypotensive, tachycardic, no urine output
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Blood loss Soaked raytec=50 cc Soaked lap=100 cc Coke can=350 cc
2 cups=500 cc Weigh to measure
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Incidence of hemorrhage
1-5% of deliveries and increasing a result of atony Developed world 1/100,000 deliveries Third world 1/1,000 deliveries After delivery bleeding slows as a result of Uterine contraction Local PA-1 from decidua and clotting factors Any alteration of above results in hemorrhage
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Uterine atony Causes 80% of postpartum hemorrhage
Immediate most common Delayed most likely from retained products of conception Uterus not palpable postpartum
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Treatment of atony Massage: external vs bimanual
Confirm no retained placental or membrane products Empty the bladder IV access if none, and bolus IV fluids Medications Oxytocin Misoprostol Methyl ergonovine Hemabate/carboprost
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Surgical treatment OB Alert/Massive transfusion protocol
Laparotomy: ligation of uterine arteries B Lynch procedure Other surgical control of atony Uterine balloon or packing Hysterectomy Interventional radiology
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B Lynch Procedure
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Risk factors for Atony Induction of labor
Prolonged labor or precipitous delivery Over-distended uterus: macrosomia, multiples, polyhydramnios etc… Prior hemorrhage*** Preeclampsia, abruption, previa, trauma Grand multiparity Coagulopathy Infection
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Delayed hemorrhage Usually retained tissue Other risk factors Evacuate
Increased likelihood of infection Asherman’s syndrome risk
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Anatomic causes for bleeding
Cervical lacerations Vaginal lacerations Vaginal hematoma Uterine inversion Cause Replacement medication
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Placenta accreta Abnormal decidualization allow villi invade myometrium Accreta=myometrial superficial invasion Increta=deep myometrial invasion Percreta=serosal invasion and beyond Incidence: In /30,000 pregnancies 1980 1/2,500 1990 1/500
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Placenta percreta
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Risk factors Location of implantation: lower uterine segment, cervix, cornua Scars in decidua: c-section, myomectomy, multiple D&C’s, Asherman’s Syndrome, septum resection Uterine anomalies Grand multiparity
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Accreta incidence One prior section=0.3% Two prior sections=0.6%
Three prior sections=2.4% If concurrent previa: No scar 1-5% One section % Two sections % Three sections >40%
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Diagnosis of accreta Antepartum ultrasound, confirm with MRI Treatment
Prior to delivery How to deliver When to deliver Discovery after vaginal delivery
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Uterine rupture With prior one low transverse c-section, incidence <1% With two prior LTV c-sections? With classical c-section? First sign of uterine rupture in trial of labor or VBAC? Trauma Drug use/abuse
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Placenta Previa “________” third trimester vaginal bleeding
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Placenta previa Complete central, partial, marginal vs low lying
Incidence at term 1%, in second trimester?
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Risk factors for previa
Prior section Prior uterine surgery: D&C’s or myomectomies, septum resections etc… Increasing parity Multiple gestation Prior previa
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Management of previa Risk to fetus: IUGR, stillbirth, prematurity
Preterm labor risk Mode of delivery….? Timing of delivery: No bleeding With bleeding At hemorrhage… Steroid use Magnesium sulfate neuroprotection Historic “double set-up”
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Placental abruption “____________” third trimester vaginal bleeding
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Placental abruption Marginal, concealed, complete
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