1. Anatomy and Physiology of Diverticular Disease

2. 2 Types
True- saclike herniation of the entire bowel
False (Pseudodiverticula)- only a protrusion of the muscosa through the muscularis propria of the colon
Most common type= pseudodiverticulum

3. Mostly occurs in sigmoid colon
Relative high pressure zone within muscular sigmoid
Higher amplitude contractions +
constipated high-fat content stool within sigmoid lumen
= diverticula

4. Protrusion in vasa recti penetrates through the muscularis propria
Results in a break in the integrity of the colonic wall
Diverticulitis- inflammation of a diverticulum
Due to retention of particulate material within diverticular sac
Formation of fecalith
Perforation or bleeding due to compression or erosion of the vasa recti