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Business Model Canvas Venture Studio Entrepreneurs Bootcamp Von Allmen Center for Entrepreneurship September 15, 2016
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A novel therapeutic approach to disorders of the central nervous system
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Novoron Bioscience, Inc.
Founded in 2013 Spin-out from UC San Diego Develop first regenerative therapy for spinal cord injury Raised >$1.25 MM in non-dilutive grants from NIH Selected to participate in the inaugural NIH
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Business Model Method or process by which one receives appropriate compensation for providing value to a customer.
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Business Model Method or process by which one receives appropriate compensation for providing value to a customer
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Front of the House
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Back of the House Front of the House
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Light Flexible Framework
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Heavy Rigid Wrong
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A startup is not a large company in miniature.
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“Everybody has a plan until they get punched in the face
“Everybody has a plan until they get punched in the face.” – Mike Tyson
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Entrepreneur Product Manager
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Technical Failure Market Failure
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Value Proposition NOT your product NOT your product’s features
Your product/idea has NO intrinsic value Cultural concept
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Value Proposition Better Faster Cheaper Culture
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Molecule capable of antagonizing LRP1 and reducing RhoA activation in neuronal cell types after a traumatic injury to the spinal cord
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Drug-like molecule Neuroregeneration
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Drug-like molecule Neuroregeneration
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Drug-like molecule Neuroregeneration Ability to walk Sphincter/bladder control Sensation
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Drug-like molecule Neuroregeneration Ability to walk Sphincter/bladder control Sensation
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Drug-like molecule Neuroregeneration Ability to walk Sphincter/bladder control Sensation BETTER Recovery CHEAPER Healthcare costs
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Customer Segments Who is paying you for your value?
Customers are human beings Three roles of a customer Decide Pay Use Be as specific as possible
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BETTER Recovery Spinal cord injury patients CHEAPER Healthcare costs
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BETTER Recovery Spinal cord injury patients Doctors CHEAPER Healthcare costs
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BETTER Recovery Spinal cord injury patients Doctors CHEAPER Healthcare costs Insurance Co.
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Get out of the building!
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BETTER Recovery Spinal cord injury patients Doctors CHEAPER Healthcare costs Insurance Co.
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BETTER Recovery Spinal cord injury patients Doctors CHEAPER Healthcare costs Insurance Co.
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Channels
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Channels Direct Indirect
Farmer’s market Trade expo Cold call Indirect Wholesale/Retail Own store Internet Affiliates/Partners Multi-sided market (local newspaper, Facebook)
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BETTER Recovery Patients Doctors Insurance Co. CHEAPER Healthcare costs Advertising Direct
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Customer Relationships
How do we interact with our customers to provide value (i.e. receive revenue)? Examples Transactional (automated?) Add-on Community Personal assistance
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BETTER Recovery Personal Patients Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Advertising Direct
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Key Activities What Key Activities do our Value Propositions require?
Our Distribution Channels? Customer Relationships? Revenue Streams? Categories Production Creation Problem Solving
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FDA approval BETTER Recovery Personal Patients Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Advertising Direct
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FDA approval BETTER Recovery Personal Patients Phase 3 Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Advertising Direct
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FDA approval BETTER Recovery Personal Patients Phase 3 Phase 2 Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Advertising Direct
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FDA approval BETTER Recovery Personal Patients Phase 3 Phase 2 Doctors SCI Community Phase 1 Insurance Co. CHEAPER Healthcare costs Advertising Direct
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FDA approval BETTER Recovery Personal Patients Phase 3 Phase 2 Doctors SCI Community Phase 1 Insurance Co. IND CHEAPER Healthcare costs Advertising Direct
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FDA approval BETTER Recovery Personal Patients Phase 3 Phase 2 Doctors SCI Community Phase 1 Insurance Co. IND Toxicology CHEAPER Healthcare costs Manufacturing Advertising Direct
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Key Resources What Key Resources do our Value Propositions require?
Our Distribution Channels? Customer Relationships? Revenue Streams? Categories Physical Intellectual (brand, patents, data) Human Financial
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FDA approval BETTER Recovery Personal Patients Clinical Trial IND Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Lab Space Advertising Direct
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FDA approval BETTER Recovery Personal Patients Clinical Trial IND Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Lab Space Advertising ClinDev Team Direct Pre-Clin Team
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FDA approval BETTER Recovery Personal Patients Clinical Trial IND Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Lab Space Advertising ClinDev Team Direct Pre-Clin Team Money
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FDA approval BETTER Recovery Personal Patients Clinical Trial IND Doctors SCI Community Insurance Co. CHEAPER Healthcare costs Lab Space Advertising ClinDev Team Direct Pre-Clin Team Money Patents Data
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Key Partners Who are our Key Partners? Who are our key suppliers?
Which Key Resources are we acquiring from partners? Which Key Activities do partners perform?
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FDA approval Patent Law BETTER Recovery Personal Patients Clinical Trial Consultants IND Doctors CRO SCI Community Insurance Co. CMO FIPCO CHEAPER Healthcare costs Lab Space Advertising Team Direct Money IP
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FDA approval Patent Law BETTER Recovery Personal Patients Clinical Trial Consultants IND Doctors CRO SCI Community Insurance Co. CMO FIPCO CHEAPER Healthcare costs Lab Space Advertising Team Direct Money IP
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FDA approval Patent Law BETTER Recovery Personal Patients Clinical Trial Consultants IND Doctors CRO SCI Community Insurance Co. CMO FIPCO CHEAPER Healthcare costs Lab Space Advertising Team Direct Money IP
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FDA approval Patent Law BETTER Recovery Personal Patients Clinical Trial Consultants IND Doctors CRO SCI Community Insurance Co. CMO FIPCO CHEAPER Healthcare costs Lab Space Advertising Team Direct Money IP
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BETTER Recovery FIPCO CHEAPER Healthcare costs
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BETTER Recovery FIPCO Biogen Sanofi AbbVie CHEAPER Healthcare costs GSK
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BETTER Drug Candidate FIPCO Biogen Sanofi AbbVie GSK
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BETTER Drug Candidate Personal FIPCO Biogen Sanofi AbbVie GSK Direct
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IND BETTER Drug Candidate Personal FIPCO Toxicology Biogen Manufacturing Sanofi PK/PD AbbVie GSK Lab Space Direct Team Money IP
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Patent Law IND BETTER Drug Candidate Personal FIPCO Consultants Toxicology Biogen CRO Manufacturing Sanofi CMO PK/PD AbbVie GSK Lab Space Direct Team Money IP
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Cost Structure Value Driven (or Cost-Based Pricing)
1970’s GM Cost Driven (or Price-Based Costing) 1970’s Toyota Easier to identify than revenue Industry specific metrics Cost per user Cost per unit Cost per per available room
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Patent Law IND BETTER Drug Candidate Personal FIPCO Consultants Toxicology Biogen CRO Manufacturing Sanofi CMO PK/PD AbbVie GSK Lab Space Direct Team Money IP Pay for activities and resources
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Revenue Streams
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Patent Law IND BETTER Drug Candidate Personal FIPCO Consultants Toxicology Biogen CRO Manufacturing Sanofi CMO PK/PD AbbVie GSK Lab Space Direct Team Money IP Licensing Fees Up front Milestone Royalty Pay for activities and resources
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BMC – Next Steps Put together a draft of your BMC
Talk to your first customer Talk to your next 5 customers Edit your draft BMC Talk to 10 more “customers” Present your draft BMC next week Confidence intervals
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“If everything seems under control,
you're not going fast enough.” - Mario Andretti
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“… [N]o plan of operations extends with any certainty beyond the first contact with the main hostile force.” - Helmuth von moltke
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“… [N]o plan of operations extends with any certainty beyond the first contact with the main hostile force.” - Helmuth von moltke
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“… [N]o plan of operations extends with any certainty beyond the first contact with the main hostile force.” - Helmuth von moltke customers
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