1. Innate Immunity: The Immediate Response to Infection
Peter Parham
The Immune System
Fourth Edition
Chapter 2
Innate Immunity: The Immediate Response to Infection
Copyright © Garland Science 2015

2. CHAPTER CONTENTS
2-1 Physical barriers colonized by commensal microorganisms protect against infection by pathogens
2-2 Intracellular and extracellular pathogens require different types of immune response
2-3 Complement is a system of plasma proteins that mark pathogens for destruction
2-4 At the start of an infection, complement activation proceeds by the alternative pathway
2-5 Regulatory proteins determine the extent and site of C3b deposition
2-6 Phagocytosis by macrophages provides a first line of cellular defense against invading microorganismstes

3. CHAPTER CONTENTS
2-7 The terminal complement proteins lyse pathogens by forming membrane pores
2-8 Small peptides released during complement activation induce local inflammation
2-9 Several classes of plasma protein limit the spread of infection
2-10 Antimicrobial peptides kill pathogens by perturbing their membranes
2-11 Pentraxins are plasma proteins of innate immunity that bind microorganisms and target them to phagocytes

4. Innate Immunity: the Immediate Response to Infection
2-1 Physical barriers colonized by commensal microorganisms protect against infection by pathogens

5. 2-1 Physical barriers colonized by commensal microorganisms protect against infection by pathogens

6. Innate Immunity: the Immediate Response to Infection
2-2 Intracellular and extracellular pathogens require different types of immune response

7. 2-2 Intracellular and extracellular pathogens require different types of immune response

8. Innate Immunity: the Immediate Response to Infection
2-3 Complement is a system of plasma proteins that mark pathogens for destruction

9. 2-3 Complement is a system of plasma proteins that mark pathogens for destruction

10. 2-3 Complement is a system of plasma proteins that mark pathogens for destruction

11. 2-3 Complement is a system of plasma proteins that mark pathogens for destruction

12. Innate Immunity: the Immediate Response to Infection
2-4 At the start of an infection, complement activation proceeds by the alternative pathway

13. 2-4 At the start of an infection, complement activation proceeds by the alternative pathway

14. 2-4 At the start of an infection, complement activation proceeds by the alternative pathway

15. 2-4 At the start of an infection, complement activation proceeds by the alternative pathway

16. Innate Immunity: the Immediate Response to Infection
2-5 Regulatory proteins determine the extent and site of C3b deposition

17. 2-5 Regulatory proteins determine the extent and site of C3b deposition

18. Innate Immunity: the Immediate Response to Infection
2-6 Phagocytosis by macrophages provides a first line of cellular defense against invading microorganisms

19. 2-6 Phagocytosis by macrophages provides a first line of cellular defense against invading microorganisms

20. Innate Immunity: the Immediate Response to Infection
2-7 The terminal complement proteins lyse pathogens by forming membrane pores

21. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

22. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

23. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

24. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

25. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

26. 2-7 The terminal complement proteins lyse pathogens by forming membrane pores

27. Innate Immunity: the Immediate Response to Infection
2-8 Small peptides released during complement activation induce local inflammation

28. 2-8 Small peptides released during complement activation induce local inflammation

29. Innate Immunity: the Immediate Response to Infection
2-9 Several classes of plasma protein limit the spread of infection

30. 2-9 Several classes of plasma protein limit the spread of infection

31. Innate Immunity: the Immediate Response to Infection
2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

32. 2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

33. 2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

34. 2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

35. 2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

36. 2-10 Antimicrobial peptides kill pathogens by perturbing their membranes

37. Innate Immunity: the Immediate Response to Infection
2-11 Pentraxins are plasma proteins of innate immunity that bind microorganisms and target them to phagocytes

38. 2-11 Pentraxins are plasma proteins of innate immunity that bind microorganisms and target them to phagocytes