1. Molecular Immunology
Saverio Minucci

2. General informations PPT slides Exams: Official books: none X info:
home page:
Click on “didattica” :
Anche su ARIEL
Exams:
team presentation of one paper related to the topics discussed during the lessons
1 written test at the end of the course (open essay: 1 topic of your choice, 1 topic chosen by me)
Official books: none
Abbas/Lichtman (Basic Immunology- or italian translation)
Pier/Lyczak/Wetzler (Immunology, infection and immunity –or italian translation)
Whatever…
X info:

3. Examination dates - 25 gennaio 12.00-14.00 aula da definire
- 08 febbraio aula da definire
- 22 febbraio aula da definire
- 15 giugno aula da definire
- 28 giugno aula da definire
- 12 luglio aula da definire
- 30 settembre aula da definire

4. A few questions for you…
What’s the difference between innate and adaptive immunity?
What can you say about innate immunity
Describe phagocytosis
How is the phagocyte attracted by its target?
How many types of adaptive immune responses do you know?
Can you give me one example of passive immunity?

5. Let’s define together the cardinal features of adaptive immune responses
Specificity
Diversity
Memory
Non reactivity to self

6. Adaptive immune response
What is a “naïve” T (or B) cell?
How is it that immune cells are able to avoid killing “self” cells?
Activated immune cell becomes either an…….or a ……….cell
What is the difference between a CD4+ and a CD8+ cell?
Which is the cell that is the main producer of antibodies?

7. Lymphocytes What’s the CD nomenclature?
What is the main difference among B and T lymphocytes?
Which are the main classes of effector T lymphocytes?
What is an APC? What’s the name of the most important class of APCs?

8. Phases of adaptive response
Antigen recognition
Lymphocyte activation
Effector Phase

9. Response to infective agents: an example

10. Topics to be addressed in the course
Vaccines
Autoimmune diseases
Allergy
Immunological reactions against tumors
Transplantation
AIDS and Kaposi sarcoma