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AIM: How are Organic and Inorganic Compounds Classified?
Topic: BIOCHEMISTRY AIM: How are Organic and Inorganic Compounds Classified? Do Now: C12H22O11 Element or Compound? If compound how many elements and how many atoms of each element are there? What type of formula is this? HW: Please Print out Review sheet for Quarterly and make sure to study all info – Bring this sheet to class tomorrow.
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ALL LIVING THINGS CONTAIN BOTH ORGANIC AND INORGANIC COMPOUNDS!
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Compound that contains BOTH Carbon AND Hydrogen
What is an organic compound? Compound that contains BOTH Carbon AND Hydrogen Makes up living things CH4 - Organic C6H12O6 - Organic CO2 – Not Organic – Does not contain H
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Compound that DOES NOT contain both Carbon and Hydrogen together
What is an inorganic compound? Compound that DOES NOT contain both Carbon and Hydrogen together H2O H2SO4 CO2 NaCl These are all INORGANIC
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WATER:
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SUGAR:
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4 Organic Cmpd Groups CARBOHYDRATES LIPIDS PROTEINS NUCLEIC ACIDS
ORGANIC COMPOUNDS 4 Organic Cmpd Groups CARBOHYDRATES LIPIDS PROTEINS NUCLEIC ACIDS
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MONOSACCHARIDE: GLUCOSE
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MONOSACCHARIDE: GALACTOSE
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MONOSACCHARIDE: FRUCTOSE
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MALTOSE DISACCHARIDE:
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3. POLYSACCHARIDE Poly = many sugars = Starch Many rings joined together
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Dehydration Synthesis
The process: “Putting molecules together and Releasing water” Water is a product (right side of the arrow) Monosaccharide + Monosaccharide Disaccharide + Water
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For carbohydrates: mono + mono disaccharide + water
+ H2O + mono + mono disaccharide + water glucose + glucose maltose water
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WATER
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+
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Hydrolysis The process of “Splitting molecules with the Addition of water” Breaking things down: ex. Digestion Water is a reactant (left side of the arrow) Disaccharide + Water = Mono + Mono
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For carbohydrates: Disaccharide + water mono + mono
+ H2O + Disaccharide water mono + mono maltose water glucose + glucose
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FUNCTIONS 1. energy storage (secondary source of energy) 2. protects organs in the body 3. insulates the body 4. makes up cell membranes
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Dehydration synthesis of lipids
1 glycerol + 3 fatty acids lipid + water
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1 molecule of fat
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Hydrolysis of lipids Lipid + water 1 glycerol + 3 fatty acids
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LIPIDS THAT ARE SOLID AT ROOM TEMP CALLED FAT
LIPIDS THAT ARE LIQUID AT ROOM TEMP CALLED OIL
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SATURATED VS. UNSATURATED
IF FAT CONTAINS SINGLE BONDS THROUGHOUT STRUCTURE, IT IS SATURATED
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SATURATED VS. UNSATURATED
IF FAT CONTAINS DOUBLE BONDS THROUGHOUT STRUCTURE, IT IS UNSATURATED
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UNSATURATED FATS ALLOWS THE BODY TO DIGEST THE FAT EASIER
UNSATURATED FATS ALLOWS THE BODY TO DIGEST THE FAT EASIER. THE DOUBLE BOND IS EASIER TO BE BROKEN DOWN & DIGESTED DOUBLE BOND HEALTHIER TO EAT
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3. Proteins Elements: C-H-O-N Building Blocks: Amino Acids (aa)
There are 20 different kinds of aa’s The order of the aa’s determines the shape of the protein and the shape determines the function of the protein. Examples: All enzymes & hormones & antibodies are PROTEINS therefore made of aa’s
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Ex. Hemoglobin is a Protein
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Ex. Antibodies (immune system)
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AMINO ACIDS
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Amino acids Building Blocks Variable group Carboxyl group Amino group
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Serine Cysteine Leucine
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Dehydration Synthesis of Proteins
Amino acid + amino acid Dipeptide + water PEPTIDE BOND Dipeptide Amino acid Amino acid
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2 amino acids joined together
Dipeptide 2 amino acids joined together Peptide bond
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Hydrolysis of Proteins
Dipeptide + water amino acid + amino acid PEPTIDE BOND + Dipeptide Amino acid Amino acid
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AMINO ACIDS NEW BOND DEHYDRATION
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2 AMINO ACIDS FORM A DIPEPTIDE
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***Blueprints of Life***
4. Nucleic Acids Elements: C-H-O-N-P Building Blocks: Nucleotides Function: Hereditary Material Ex. DNA & RNA ***Blueprints of Life***
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COMPOSED OF THREE PARTS:
-SUGARS -PHOSPHATE GROUPS -NITROGENOUS GROUPS
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Building blocks = NUCLEOTIDE
phosphate Nitrogen base sugar
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NITROGENOUS BASES 5 Bases DNA: A-T & G-C RNA: A-U & G-C
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NITROGENOUS BASE BOND RIBOSE PHOSPHATE
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IN A DNA STRAND, THE BASES PAIR UP AS FOLLOWS:
C - G A - T IN A RNA STRAND: A - U
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FINALLY THE ALPHA HELIX
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ALL ENZYMES Are PROTEINS Are Made of AA’s Are Polypeptides
Are Made in the Ribosomes Have a specific shape Are specific Work on specific substrates Names end in ASE Are organic catalysts
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Enzyme = Organic Catalyst What is a Catalyst?
Enzymes Enzyme = Organic Catalyst What is a Catalyst?
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Speed up the rate of a reaction but they themselves do not change.
Catalysts
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Names end in –ase Examples: Lipid – Lipase Protein – Protease
Maltose – Maltase Lactose – Lactase
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Binds with an enzyme in order for the reaction to occur
What is being broken down or put together What is a substrate?
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What is an active site? Where the enzyme and substrate touch – where the actual chemical reaction occurs.
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Enzyme-substrate complex
Active Site Enzyme Substrate Enzyme-substrate complex
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What Factors Affect Enzyme Activity?
Temperature pH Amount of Substrate & Enzyme
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Optimal Temp 98.6 F = 37 C Best Temp. for enzymes to work
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37°C
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If temp rises above this DENATURATION occurs
Denaturation = enzyme changes shape substrate cannot fit with active site REACTION DOES NOT HAPPEN
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2. pH & Enzyme activity pH = how basic or acidic a liquid is. A pH of 1-6 is acidic, 7 is neutral and 8-14 is basic. Most places in the body are neutral so most Enzymes work best at a pH of 7.
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Optimum pH = 7 1 14 7 pH
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HOWEVER: Some enzymes work best in other pH’s.
or basic conditions
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(All the gas pumps are full and cars have to wait to get gas now)
Increasing substrate amount will increase reaction rate until all enzymes are occupied- then reaction is at maximum rate. (All the gas pumps are full and cars have to wait to get gas now) 3. Substrate concentration
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THE END Increasing substrate increases the enzymes reaction rate
Max Rate THE END
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NITROGENOUS BASES DIVIDED INTO TWO CATEGORIES: PYRIMIDINES PURINES &
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TWO TYPES WHICH EXIST IN DNA & RNA
PURINES TWO TYPES WHICH EXIST IN DNA & RNA ADENINE (A) AND GUANINE (G)
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PYRIMIDINES THERE ARE 3 TYPES CYTOSINE (C) IN DNA & RNA THYMINE (T) ONLY IN DNA URACIL (U) ONLY IN RNA
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SHAPE OF DNA IN 1953, WATSON AND CRICK DEDUCED THE SHAPE OF THE DNA AS AN ALPHA HELIX OR A SPIRAL STAIRCASE
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LADDER HAS A SUGAR & PHOSPHATE BACKBONE: OUTSIDE
SHAPE OF DNA LADDER HAS A SUGAR & PHOSPHATE BACKBONE: OUTSIDE THE NITROGENOUS BASES:IN THE MIDDLE & ARE HELD TOGETHER BY WEAK HYDROGEN BONDS
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ATOMS: Compromise the element. Contain protons, neutrons and electrons
DEFINITIONS: ATOMS: Compromise the element. Contain protons, neutrons and electrons
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ELEMENTS: A substance that can not be broken down
DEFINITIONS: ELEMENTS: A substance that can not be broken down
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COMPOUND: Two or more elements combined chemically
DEFINITIONS: COMPOUND: Two or more elements combined chemically
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DEFINITIONS: BONDING: the formation of compounds resulting from a chemical bond. Two types of bonds covalent (sharing electrons) and ionic (transfer of electrons)
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ATOMS CONTAIN PROTONS, ELECTRONS AND NEURTONS
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CAN BE TRANSFERRED (ionic) OR SHARED (covalent) DURING A BOND
ELECTRONS ELECTRONS CAN BE TRANSFERRED (ionic) OR SHARED (covalent) DURING A BOND
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SATURATED FATS ARE CONVERTED INTO CHOLESTEROL 2 TYPES OF CHOLESTEROLS:
HDL’s: GOOD TYPE OF CHOLESTEROL LDL’s: DANGEROUS TYPE OF CHOLESTEROL ANIMAL PRODUCTS: MILK & MEATS ARE HIGH IN SATURATED FATS FISH, VEGETABLES AND MARGARINE: HIGH IN UNSATURATED FATS
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BOND BETWEEN 2 AMINO ACIDS IS THROUGH A PEPTIDE BOND BETWEEN
THE CARBON AND NITROGEN
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1. OCCUR BETWEEN CARBON OF ONE AMINO ACID AND NITROGEN OF AN ANOTHER
PEPTIDE BONDS: 1. OCCUR BETWEEN CARBON OF ONE AMINO ACID AND NITROGEN OF AN ANOTHER 2. LEAD TO DIPEPTIDES AND POLYPEPTIDES 3. OCCUR DUE TO DEHYDRATION SYNTHESIS
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Peptide Bond C N O H
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DNA & RNA LACK OF OXYGEN
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