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Mon: Labor Day Tue: Sci. method Test Wed/Thurs: Organic compound lab Fri: What’s in my food Bell warm up 09/10/10 What do these foods contain? Options: carbohydrate/ lipid/protein/nucleic acid A B C
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Organic Chemistry
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Uses of Organic Molecules
Americans consume an average of 140 pounds of sugar per person per year Cellulose, found in plant cell walls, is the most abundant organic compound on Earth
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Uses of Organic Molecules
A typical cell in your body has about 2 meters of DNA A typical cow produces over 200 pounds of methane gas each year
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Water Water is used in most reactions in the body
About percent of an organism is water Water is used in most reactions in the body Water is called the universal solvent
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Water Properties Polarity Cohesiveness Adhesiveness Surface Tension
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Carbon-based Molecules
Although a cell is mostly water, the rest of the cell consists mostly of carbon-based molecules Organic chemistry is the study of carbon compounds
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Carbon is a Versatile Atom
It has four electrons in an outer shell that holds eight Carbon can share its electrons with other atoms to form up to four covalent bonds
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What makes carbon special?
Carbon has 4 electrons in its outer energy level, so it has to form 4 bonds to become stable. Carbon can bond with wide variety of other things.
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What makes carbon special?
Carbon has 4 electrons in its outer energy level, so it has to form 4 bonds to become stable. Carbon can bond with wide variety of other things.
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Hydrocarbons The simplest carbon compounds …
Contain only carbon & hydrogen atoms
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Carbon can use its bonds to::
Attach to other carbons Form an endless diversity of carbon skeletons
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The hydrocarbons of fat molecules provide energy for our bodies
Large Hydrocarbons: Are the main molecules in the gasoline we burn in our cars The hydrocarbons of fat molecules provide energy for our bodies
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Shape of Organic Molecules
Each type of organic molecule has a unique three-dimensional shape The shape determines its function in an organism
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Functional Groups are:
Groups of atoms that give properties to the compounds to which they attach Lost Electrons Gained Electrons
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Common Functional Groups
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Giant Molecules - Polymers
Large molecules are called polymers Polymers are built from smaller molecules called monomers Biologists call them macromolecules
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Examples of Polymers Proteins Lipids Carbohydrates Nucleic Acids
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Monomers are the building blocks of organic molecules Monomer + monomer + monomer etc = polymer
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Most Macromolecules are Polymers
Polymers are made by stringing together many smaller molecules called monomers Nucleic Acid Monomer
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This process joins two sugar monomers to make a double sugar
Linking Monomers Cells link monomers by a process called dehydration synthesis (removing a molecule of water) Remove H H2O Forms Remove OH This process joins two sugar monomers to make a double sugar
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When monomer is joined to another monomer, there is loss of water : dehydration synthesis
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Breaking Down Polymers
Cells break down macromolecules by a process called hydrolysis (adding a molecule of water) Water added to split a double sugar
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When polymer beaks down to form monomer, WATER is added –HYDROLYSIS That is water is added to split the two sugars
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Bellwarm up: Root words quiz
1. Monosaccharide : mono / saccharide ___________ / _____________ 2. hydrolysis : hydro / lysis _____ / _______ 3. polymer : poly / mer __________ / ___________ 4. dehydration: de / hydro / tion _______ / _____ / _______ 5. macromolecule: macro / molecule _______ / molecule 6. Lactose : lact / ose _____ / _____ 7 Synthesis : Synthesis _________
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Root word quiz 0 = 100% -1 = 93% -2 = 86% -3 = 79% -4 = 72% -5 = 65%
-6 = 58% -7 = 51% -8 = 44% -9 = 37% -10 = 30%
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Macromolecules in Organisms
There are four categories of large molecules in cells: Carbohydrates Lipids Proteins Nucleic Acids
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Question: Name the 4 organic molecules or biomolecules
Carbohydrates Lipids Proteins Nucleic Acids
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Question: Monomer + monomer = ______________ POLYMER
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Q: Water is lost when monomers joins to form polymer . True or false
True Dehydration synthesis De= without Hydro= water tion = condition or state of
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Carbohydrates Carbohydrates include:
Small sugar molecules in soft drinks Long starch molecules in pasta and potatoes
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Components of Carbohydrates are carbon hydrogen and Oxygen
Basic building block is a monosaccharide Two monosaccharide form a dissacharide Types: Carbohydrate include 1.Monosaccharide (building block) 2. Disacharide 3. Polysaccharide (polymer)
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Monosaccharides: Called simple sugars
Include glucose, fructose, & galactose Have the same chemical, but different structural formulas C6H12O6
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Monosaccharides (simple sugar)
Glucose is found in sports drinks Fructose is found in fruits Honey contains both glucose & fructose Galactose is called “milk sugar”
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Isomers Glucose & fructose are isomers because they’re structures are different, but their chemical formulas are the same
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In aqueous (watery) solutions, monosaccharides form ring structures
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Cellular Fuel Monosaccharides are the main fuel that cells use for cellular work ATP
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Disaccharides A disaccharide is a double sugar
They’re made by joining two monosaccharides Involves removing a water molecule (dehydration)
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Common disaccharides include:
Sucrose (table sugar) Lactose (Milk Sugar) Maltose (Grain sugar)
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Disaccharides Maltose is composed of 2 glucose molecules
Sucrose is composed of glucose + fructose Maltose is composed of 2 glucose molecules Lactose is made of galactose + glucose GLUCOSE
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Polysaccharides Complex carbohydrates
Composed of many sugar monomers linked together Polymers of monosaccharide chains
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Examples of Polysaccharides
Glucose Monomer Starch Glycogen Cellulose
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Starch Starch is an example of a polysaccharide in plants
Plant cells store starch for energy Potatoes and grains are major sources of starch in the human diet
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Glycogen Glycogen is an example of a polysaccharide in animals
Animals store excess sugar in the form of glycogen Glycogen is similar in structure to starch
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Q: in what form do animals store excess energy?
GLYCOGEN
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Cellulose Cellulose is the most abundant organic compound on Earth
It forms cable-like fibrils in the tough walls that enclose plants It is a major component of wood It is also known as dietary fiber
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Cellulose SUGARS
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Dietary Cellulose Most animals cannot derive nutrition from fiber
They have bacteria in their digestive tracts that can break down cellulose
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Function of carbohydrate
The main function is to store energy In plant energy stored as STARCH In animal energy stored as GLYCOGEN
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_______________ is the most abundant organic compound on Earth
A. Protein B. carbohydrate c. Lipid D. Nucleic acid
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Sugars in Water Simple sugars and double sugars dissolve readily in water WATER MOLECULE They are hydrophilic, or “water-loving” SUGAR MOLECULE
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Bell warm up 09/14/10 Plants stores energy in form of________
A. Glycogen B. starch
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Lipid Lipids
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Lipids Lipids are hydrophobic –”water fearing” Do NOT mix with water
Includes fats, waxes, steroids, & oils FAT MOLECULE
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Lipid Components The components of lipids are Carbon Hydrogen Oxygen
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Lipids Building blocks
Fatty acid + glycerol
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Types of Fatty Acids Unsaturated fatty acids have less than the maximum number of hydrogens bonded to the carbons (a double bond between carbons) Saturated fatty acids have the maximum number of hydrogens bonded to the carbons (all single bonds between carbons)
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Types of Fatty Acids Single Bonds in Carbon chain
Double bond in carbon chain
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Buiding block of lipid: fatty acid and glycerol
Monomer of lipids Composed of Glycerol & 3 fatty acid chains Glycerol forms the “backbone” of the fat Organic Alcohol
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Triglyceride Fatty Acid Chains Glycerol
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Fats in Organisms Most animal fats have a high proportion of saturated fatty acids & exist as solids at room temperature (butter, margarine, shortening)
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Types/ examples Oils- liquid at room temperature Fats- solid at room temperature Waxes Steroid
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Oils Most plant oils tend to be low in saturated fatty acids & exist as liquids at room temperature (oils)
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Fats Dietary fat consists largely of the molecule triglyceride composed of glycerol and three fatty acid chains Fatty Acid Chain Glycerol Dehydration links the fatty acids to Glycerol
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Steroids The carbon skeleton of steroids is bent to form 4 fused rings Cholesterol Cholesterol is the “base steroid” from which your body produces other steroids Estrogen Testosterone Estrogen & testosterone are also steroids
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Waxes Solid at room temperature
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Steroids They are variants of testosterone
Some athletes use them to build up their muscles quickly They can pose serious health risks
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Function of Lipids Fats store energy, help to insulate the body, and cushion and protect organs
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Proteins Components: Proteins are made up of Carbon Hydrogen Oxygen
Nitrogen
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Building block Proteins are polymers made of monomers called amino acids That is amino acids are the building blocks of proteins
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Four Types of Proteins Storage Structural Contractile Transport
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20 Amino Acid Monomers
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Structure of Amino Acids
group Carboxyl group Amino acids have a central carbon with 4 things boded to it: R group Amino group –NH2 Carboxyl group -COOH Hydrogen -H Side groups Side group -R Serine-hydrophillic Leucine -hydrophobic
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Linking Amino Acids Cells link amino acids together to make proteins
Carboxyl Cells link amino acids together to make proteins Amino Side Group The process is called dehydration synthesis Dehydration Synthesis Peptide bonds form to hold the amino acids together Peptide Bond
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Function Function Proteins are used to build cells
act as hormones & enzymes, and do much of the work in a cell
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Enzymes Are biological catalysts- they alter rate of chemical reaction
Thousands of different enzymes exist in the body Enzymes control the rate of chemical reactions by weakening bonds, thus lowering the amount of activation energy needed for the reaction
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Enzymes Enzymes are globular proteins.
Their folded conformation creates an area known as the active site. The nature and arrangement of amino acids in the active site make it specific for only one type of substrate.
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Enzyme + Substrate = Product
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How the Enzyme Works Enzymes are reusable!!!
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Primary Protein Structure
The primary structure is the specific sequence of amino acids in a protein Amino Acid
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Protein Structures Secondary protein structures occur when protein chains coil or fold When protein chains called polypeptides join together, the tertiary structure forms In the watery environment of a cell, proteins become globular in their quaternary structure
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Protein Structures Hydrogen bond Pleated sheet Polypeptide
(single subunit) Amino acid (a) Primary structure Hydrogen bond Alpha helix (b) Secondary structure (c) Tertiary structure (d) Quaternary structure
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Denaturating Proteins
Changes in temperature & pH can denature (unfold) a protein so it no longer works Cooking denatures protein in eggs Milk protein separates into curds & whey when it denatures
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Changing Amino Acid Sequence
Substitution of one amino acid for another in hemoglobin causes sickle-cell disease 2 1 3 6 4 5 (a) Normal red blood cell Normal hemoglobin 2 1 3 6 4 5 (b) Sickled red blood cell Sickle-cell hemoglobin
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Nucleic Acids Nucleic acids are polymers of nucleotides That is
Nucleotides are the building blocks of nucleic acid Nitrogenous base (A,G,C, or T) Phosphate group Thymine (T) Sugar (deoxyribose) Phosphate Base Sugar Nucleotide
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Bases Each DNA nucleotide has one of the following bases: Adenine (A)
Thymine (T) Cytosine (C) Adenine (A) Guanine (G) Thymine (T) Cytosine (C) Adenine (A) Guanine (G)
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Components of nucleic acid
Phosphate group Nitrogenous base Sugar group
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Bell warm up 10/14/08 Plants stores energy in form of________
Animals store energy in form of _______
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Nucleic Acids
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Building block Nucleotides are the building blocks of nucleic acid
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Nucleotide Monomers Form long chains called DNA
Backbone Form long chains called DNA Nucleotide Nucleotides are joined by sugars & phosphates on the side Bases DNA strand
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There are 2 types of Nucleic acid
DNA RNA
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DNA Two strands of DNA join together to form a double helix Base pair
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RNA – Ribonucleic Acid Ribose sugar has an extra –OH or hydroxyl group
Nitrogenous base (A,G,C, or U) Ribose sugar has an extra –OH or hydroxyl group Uracil Phosphate group It has the base uracil (U) instead of thymine (T) Sugar (ribose)
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Nucleic Acids function
Store hereditary information Contain information for making all the body’s proteins Two types exist --- DNA & RNA
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Summary of Key Concepts
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Macromolecules
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Macromolecules
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List the four Organic compounds.
Bell warm up Thurs 10/03/07 Question List the four Organic compounds.
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Which of the following is NOT one of the 4 organic molecules?
nucleic acid carbohydrate lipid isomerism
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How many electrons does carbon have in its’ outermost shell?
A. one B. two C. three D. four
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DNA stores A. fat B. genetic information C. carbohydrates D protein
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A monosaccharide is a A. carbohydrate B. lipid C. nucleic acid D. protein
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The two types of nucleic acids are
A. transpiration and evaporation B. DNA and RNA C. lipids and sugars D. glucose and glycogen
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What is the main function of a carbohydrate?
It stores energy. It makes skin and muscle. It digests fat. It carries genetic information
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Animals store excess glucose as
glycogen. starch. monosaccharide. cellulose
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Glycerol and fatty acids are the building blocks for
proteins. Lipids. nucleic acids. polysaccharides.
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The following structure represents a
A. carbohydrate B. Lipid (triglyceride) C. protein D. nucleic acid
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The building blocks of proteins are
A. 1 glycerol and 3 fatty acids. B. monosaccharides polypeptides. amino acids
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What is the function of DNA?
storing heredity information providing energy acts as enzyme
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Which of the following is a lipid?
A. Oils B. Sugars C. Proteins D. Starches
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Oils are solid at room temperature True or False
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The structure below is a a. carbohydrate b. lipid c. protein d
The structure below is a a. carbohydrate b. lipid c. protein d. nucleic acid
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The structure below is a a. carbohydrate b. lipid c. protein d
The structure below is a a. carbohydrate b. lipid c. protein d. nucleic acid
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The structure below is a a. carbohydrate b. lipid c. protein d
The structure below is a a. carbohydrate b. lipid c. protein d. nucleic acid
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The structure below is a a. carbohydrate b. lipid c. protein d
The structure below is a a. carbohydrate b. lipid c. protein d. nucleic acid
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The structure below is a a. monosacharide b. polysacharide
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The structure below is a a. monosacahride b. polysacharide0
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