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Assessment of inflammation in noninfectious chronic maxillary sinusitis  Pascal Demoly, MDa, Louis Crampette, MDb, Michel Mondain, MDb, Alison M. Campbell,

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Presentation on theme: "Assessment of inflammation in noninfectious chronic maxillary sinusitis  Pascal Demoly, MDa, Louis Crampette, MDb, Michel Mondain, MDb, Alison M. Campbell,"— Presentation transcript:

1 Assessment of inflammation in noninfectious chronic maxillary sinusitis 
Pascal Demoly, MDa, Louis Crampette, MDb, Michel Mondain, MDb, Alison M. Campbell, PhDa, Nadine Lequeuxc, Ingrid Enander, PhDd, Lawrence B. Schwartz, MDe, Bernard Guerrier, MDb, François B. Michel, MDa, Jean Bousquet, MD, PhDa  Journal of Allergy and Clinical Immunology  Volume 94, Issue 1, Pages (July 1994) DOI: / (94) Copyright © 1994 Mosby, Inc. Terms and Conditions

2 FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

3 FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

4 FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

5 FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

6 FIG. 1 Levels of ECP, histamine, MPO, tryptase, and PGD2 in sinus lavage fluids from patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

7 FIG. 2 Immunohistochemical analysis of ECP (EG1) in a patient with sinusitis and CAR. (Original magnification ×400.) Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

8 FIG. 3 Eosinophils (EG1- and EG2-positive cells) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

9 FIG. 4 Immunohistochemical analysis of tryptase (G3) in a patient with sinusitis and CAR. (Original magnification ×400.) Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

10 FIG. 5 Mast cells in the submucosa and intraepithelium (G3-positive cells) in patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

11 FIG. 5 Mast cells in the submucosa and intraepithelium (G3-positive cells) in patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

12 FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

13 FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

14 FIG. 6 Neutrophils (elastase), macrophages (CD68), and T cells (CD3) in sinus biopsy specimens of patients with sinusitis and chronic allergic and nonallergic rhinitis and control subjects. Journal of Allergy and Clinical Immunology  , DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

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