1. Beta-thalassemia major. (Peripheral blood, 50 ×
Beta-thalassemia major. (Peripheral blood, 50 ×.) Microcytic, hypochromic target cells of severe beta-thalassemia. Many red blood cell shapes are bizarre, consistent with severe thalassemia. There is intense reticulocytosis, as evidenced by a large number of nucleated red blood cells in the peripheral blood. The thalassemias are hyperproductive anemias manifested by hemolysis occurring in the bone marrow compartment due to mispairing of beta and globin units. (Used, with permission, from L Damon.)
Source: Blood Disorders, Current Medical Diagnosis & Treatment 2018
Citation: Papadakis MA, McPhee SJ, Rabow MW. Current Medical Diagnosis & Treatment 2018; 2017 Available at: Accessed: September 29, 2017
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