2. Ahmed Mohamed Abd Elmajeed 99
Markers Of
Pulmoary embolism
Under the Supervision of:
Prof.Dr Hala Rashad
Made by:
Ahmed Mohamed Abd Elmajeed 99

3. Pulmonary embolism (PE)
DEF
Symptoms
Diagnosis
Cause

4. Pulmonary embolism (PE)
DEF
Symptoms
Diagnosis
Cause
is the blockage of the main artery of the lung or one of its main branches by emboli

5. Pulmonary embolism (PE)
DEF
Symptoms
Diagnosis
Cause
DVT
Deep vein thrombosis
VTE
Venous thromboembolism

7. Pulmonary embolism (PE)
DEF
Symptoms
Diagnosis
Cause
 palpitations
difficulty of breathing
chest pain on inspiration

8. Pulmonary embolism (PE)
DEF
Symptoms
Diagnosis
Cause
Signs
symptoms
Lab test
(D-Dimer )
Imaging
CT pulmonary angiography

9. markers of pulmonary embolism
D-dimer
fibrin degradation product
present in the blood after a blood clot is degraded by fibrinolysis
Name?
D-dimer concentration help diagnose thrombosis.

10. D-dimer
normally not present in plasma, except when the coagulation system has been activated
High sensitivity but low specificity ?
negative >>>>>>>rules out thrombosis
positive >>>>>>>Thrombosis or other cause

11. Units µg/mL < 0.5 Nonpregnant adult First trimester 0.05 - 0.95
Second trimester
Third trimester
µg/mL
< 0.5

12. Caoagulation cascade
Scaffold of blood clot

13. False positive readings in
Liver disease
Malignancy
Pregnancy
Recent surgery
Advanced age

14. False positive readings in
Liver disease
Malignancy
Pregnancy
Recent surgery
Advanced age

15. False positive readings in
Liver disease
Malignancy
Pregnancy
Recent surgery
Advanced age

16. False positive readings in
Liver disease
Malignancy
Pregnancy
Recent surgery
Advanced age

17. False positive readings in
Liver disease
Malignancy
Pregnancy
Recent surgery
Advanced age

18. False negative readings
if the sample is taken either too early after thrombus formation or delayed for several days
the presence of anti-coagulant because it prevents thrombus extension.

19. False negative readings
if the sample is taken either too early after thrombus formation or delayed for several days
the presence of anti-coagulant because it prevents thrombus extension.

20. 1-European heart journal 2008 2-online archive of thrombosis and hemostasis