1. Lecture 1: Definition of Nanomedicine and Nanotechnology
Contents:
New Technological Frontiers in the 21st Century
Relation of Nanomedicine to the Basic Sciences
Definition of Nanomedicine
Definition of Nanotechnology
Imaging and Treatment Modalities:
Advantages and Disadvantages
Conclusions

2. New Technological Frontiers
20th Century:
- Physics,
- Microelectronics,
- High-Speed Communications
- Transportation
21st Century:
- Nanotechnology
- Biology
- Information
- but also Energy, Environment, and Sustainability

3. Nanomedicine Relation to Basic Sciences
Biophysics
Engineering:
Optical technology
Laser technology
Nanotechnology
and so on
Interdisciplinary study
combines
Biology:
Cell biology
Cytology
Microbiology
and so on
Physics:
Optics
Thermodynamics
Kinetics
and so on
New Technology
Diagnosis and Treatment of
Diseases
Fundamental Knowledge
for
Medical Physics
Imaging
Radiation Oncology
Photodynamic Therapy
Nanomedicine

4. What is Nanomedicine?
Nanomedicine is an interdisciplinary field of science which involves physics, engineering biology, chemistry, medicine and other sciences for diagnosis and treatment of diseases by means of nanotechnology.
The ultimate goal of nanomedicine is to treat the human body at the atomic and molecular levels, and to repair a body like we repair conventional machines today.

5. Nanotechnology Defined
Video 1
Nano = Greek for “Dwarf”
Nano = “1 billionth”
Research and development at the atomic, molecular or macromolecular levels, on the length scale of approximately nanometer range . . .
. . . to create and use structures, devices and systems that have novel properties and functions because of their small and/or intermediate size
Nanotechnology involves purposeful imaging, measuring, modeling, and manipulating matter at this length scale
Source: National Nanotechnology Initiative

6. Traditional Imaging and Treatment Modalities
Radiography
Fluoroscopy
Mammography
Computed tomography
Nuclear medicine
Positron emission tomography
Magnetic resonance imaging
Chemotherapy
Magnetic field treatment
Microwave and RF treatment

7. Benefits of Conventional Clinical Modalities
Deep penetration into the body
Whole body scan
Slice scan
Fast scan
Position accuracy
Density information
Organs structure and boundaries
Extend patient life

8. Disadvantages of Conventional Clinical Modalities
Unable to detect and treat at the single cell level
Unable to detect and treat at the DNA level
Late diagnosis and treatment
Unable to detect and treat metastasis in time
Unable to carry out selective treatment on only cancer cells
Healthy tissue damage
X-rays treatment could cause a secondary cancer
Unable to treat effectively bone cancer and marrow
Unable to complete cancer cure
Recurrence occurs after the treatment
Patients eventually die
Expensive treatment
Nanomedicine
is a future medicine

9. Conclusions: Nanomedicine is a Smart Medicine
Nanomedicine is a future medicine.
Fast painless treatment.
Early diagnostics at the single cell or DNA levels.
Metastasis treatment at the cellular level.
Bone cancer treatment.
Defeat cancer for good and give full life for cancer patients.