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Xenotransplantation of Human Cord Blood Derived Unrestricted Somatic Stem Cells Rescue the Blistering Phenotype in a Murine Model of Recessive Dystrophic.

Published byClyde Stephens Modified over 7 years ago

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Presentation on theme: "Xenotransplantation of Human Cord Blood Derived Unrestricted Somatic Stem Cells Rescue the Blistering Phenotype in a Murine Model of Recessive Dystrophic."— Presentation transcript:

1 Xenotransplantation of Human Cord Blood Derived Unrestricted Somatic Stem Cells Rescue the Blistering Phenotype in a Murine Model of Recessive Dystrophic Epidermolysis Bullosa  Yanling Liao, PhD, Larisa Ivanova, PhD, Bhavishya Surapaneni, Ashlin Yahr, BA, Mitchell S. Cairo, MD  Biology of Blood and Marrow Transplantation  Volume 20, Issue 2, Pages S185-S186 (February 2014) DOI: /j.bbmt Copyright © Terms and Conditions

2 Fig 1 A. Kaplan-Meier curve comparison between untreated and a single USSC intrahepatic injection, repeated intra-hepatic USSC injection, a single subcutaneous USSC injection and USSC conditioned medium injection. P< B. Disappearance of hemorrhagic blisters in the paws of a representative RDEB mouse skin following USSC treatment. Biology of Blood and Marrow Transplantation  , S185-S186DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Fig 2 A. Time course BLI on a representative RDEB mouse that received USSC injection. B. Imaging of dissected internal organs on days 0 and 2.1, liver. 2, lung, 3, stomach and digestive system, 4, pancreas, 5, spleen, 6, heart and 7, kidney. Biology of Blood and Marrow Transplantation  , S185-S186DOI: ( /j.bbmt ) Copyright © Terms and Conditions

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