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Phagocytosis
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Macrophage lymphocyte
PMNLs Plasma cells Macrophage lymphocyte inflammation: seen here are mainly neutrophils, but there are also plasma cells, lymphocytes, and macrophages
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Cont. Inflammation GRANULOMA
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Granuloma: -It’s a type of chronic specific inflammation, characterized by accumulation of tumor like masses. -types: 1-infective, 2-non-infective.
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Granuloma: The single tubercle composed of :
1-central necrotic tissue, 2-epithellioid cells, 3-lymphocytes and plasma cells, 4-langhans cell .
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Tuberculosis -Tuberculosis , MTB or TB (short for tubercles bacillus) is infectious disease caused by Mycobacterium tuberculosis -It is usually attacks the lungs but can also affect other parts of the body. - It is spread through the air when people who have active MTB infection cough, sneeze, or spit
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1- Early T.B in lymph node:
-Pale pink rounded tubercles among blue lymphoid tissue. -the tubercle is formed of : epithelioid cells, langhans gient cells &lymphocytes.
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2- Caseating T.B in LN -Caseous is a form of biological tissue death. Necrosis (death) Tuberculosis - it is characterized by acellular pink areas of necrosis surrounded by a granulomatous inflammatory process
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3- Chronic fibrocasious T.B in lung:
-large irregular areas of caseation appearing homogenous pink surrounded by tubercles reaction an fibrous tissue.
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Bilharziasis -It is a parasite infection by a trematode worm acquired from infested water. Also known as (schistosomiasis). - it is can produce in liver, bladder, and gastrointestinal problems
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4- Bilharziasis in rectum:
Bilharzia ova deposited mainly in the submucosa -ova appear rounded or oval and yllowish refractile shell,degenerated ova are pink , while clascified ova are blue. -ova are surrounded by macrophages ,plasma cells, esinophils,lymphocytes & foreign body giant cells.
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5- Bilharziasis in Urinary Bladder:
-Bilharzia ova deposited mainly in the submucosa with less degree in other layers . -The ova surrounded by bilharzial rxn
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6- Bilharziasis in liver:
Bilharzias ova deposited in the portal tract. The ova surrounded by bilharzial rxn formed capilleries & new bile ducts.
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