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Characterisation of Myocardial Injury via T1 Mapping in Early Reperfused Myocardial Infarction and its Relationship with Global and Regional Diastolic.

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Presentation on theme: "Characterisation of Myocardial Injury via T1 Mapping in Early Reperfused Myocardial Infarction and its Relationship with Global and Regional Diastolic."— Presentation transcript:

1 Characterisation of Myocardial Injury via T1 Mapping in Early Reperfused Myocardial Infarction and its Relationship with Global and Regional Diastolic Dysfunction  Shah M. Azarisman, MBBS, MMed, PhD, Angelo Carbone, BSc, Mitra Shirazi, MBBS, FRACP, Julie Bradley, MBBS, FRACP, Karen S. Teo, MBBS, PhD, Matthew I. Worthley, MBBS, PhD, Stephen G. Worthley, MBBS, PhD  Heart, Lung and Circulation  Volume 25, Issue 11, Pages (November 2016) DOI: /j.hlc Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

2 Figure 1 (A) Cine images showing sequential short-axis slices covering the entire ventricle. (B) Imaging plane planned parallel to the mitral annular plane at the level of the mitral leaflet tips. (C) Mitral annular velocity measurement with ROI placed at anteroseptal region of the myocardium. (D) Cross-sectional PV flow is acquired by an imaging plane 1cm distal to, and parallel to the level of the PV inflow into the left atrium. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

3 Figure 2 Maximum velocity vs. time graphs characterising mitral diastolic E and A waves, mitral annular E’ and A’ waves and pulmonary systolic S and diastolic D waves. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

4 Figure 3 Microvascular obstruction as seen in T2W, LGE and T1 mapping images. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

5 Figure 4 Regional myocardial strain assessment using Harmonic Phase (HARP) analysis. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

6 Figure 5 The mean pre- and 10minute post-gadolinium T1 relaxation times of all patients at baseline. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

7 Figure 6 Pre-contrast T1 relaxation times at baseline and at 90 days.
Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

8 Figure 7 Correlation between T1 relaxation time of the infarcted segments and scar mass. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

9 Figure 8 Correlation between T1 relaxation time of the infarcted segments and the global values for diastolic dysfunction. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions

10 Figure 9 Correlation between T1 relaxation time of the infarcted segments and circumferential diastolic strain rate. Heart, Lung and Circulation  , DOI: ( /j.hlc ) Copyright © 2016 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ) Terms and Conditions


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