1. Come discover the action
@TOHealthToronto
tohealth.ca
Come discover the action

2. About TO health!
Who we are TO Health! is a promotion cooperative focused on raising the profile of the Toronto region human health & sciences cluster. Vision Together we will make the Toronto region globally renowned for its dynamic and innovative human health & sciences ecosystem, placed in the top five of global human health science clusters. Mission We will increase revenue growth opportunities for the Toronto region by attracting more risk capital, corporate investment and qualified talent to the cluster participants. ? 🔍

3. Toronto Region human health + sciences cluster
North
Downtown
“High Tech Capital”
100 ICT companies
1 university, 3 colleges
Multinational generic, digital and medical device companies
Neutraceutical and manufacturing operations
“Discovery district”
9 research hospitals, 10 community hospitals
3 universities, 3 colleges, 37 research institutes
160 biotechnology and medical device companies
east
West
“Advanced manufacturing”
Multinational generics and digital companies
Laboratories, manufacturing and warehousing operations
1 university campus, 3 hospitals
“Pill Hill”
30 multinational pharma and medical device companies
30+ small and medium biotechnology and medical device companies
Laboratories, manufacturing and warehousing operations
1 university campus, 1 college, 6 hospitals

4. Human Health + Sciences Cluster participants
Companies
Organizations
Suppliers & Services
Pharmaceuticals/ Biologics
Research/Skills Development Organizations
Specialized Business Services
Medical Devices
Innovation Organizations
Specialized Risk Capital
Industry Associations
Health Care IT
Healthcare Delivery Organizations
Private Payers
Contract Research/Mfg
Government
Patient Advocates

5. The Toronto region: A global Cluster
The Toronto region has a solid foundation for dynamic growth of the scale and scope that places it among the world’s top human health science clusters.
Source: Jones, Lang, LaSalle. Life Sciences Cluster Report 2014

6. Global clinical trials World-leading Academic & Translational research
Perfect mix of science, business and lifestyle in the only growing metro region
A centre for
Global clinical trials
World-leading Academic
& Translational research

7. World-leading Academic & Translational research
Globally recognized research universities
Toronto region Hospitals: a Driving Force for research
Globally recognized Thought leaders

8. World-leading Academic & Translational research
Globally recognized research universities
Over $1B in research funding at universities and partner hospitals
University of Toronto is the #2 university for publications and citations
9300+ life science graduates annually

9. World-leading Academic & Translational research
Toronto region Hospitals: a Driving Force for research
$840.5 million in research revenue
over 9500 researchers and research staff
277 IP disclosures and 73 commercializations
Source: 2013/14 metrics from CAHO CRF/RIM database

10. World-leading Academic & Translational research
Globally recognized Thought leaders
Cancer: Dr. Tak Mak (breast cancer), Dr. Rob Bristow (prostate cancer), Dr. Aaron Schimmer (leukemia)
Cell and regenerative medicine: Dr. Andras Nagy (viral-free iPS cells), Dr. John Dick (Blood stem cells), Dr. Michael Fehlings (spinal cord regeneration), Dr. Maria Cristina Nostro (diabetes)
Genomics: Dr. Stephen Scherer (pioneering genomic variation and genomics of autism), Dr. Dev Sidhu (protein structure and function)
Neuroscience: Dr. Sandra Black (stroke and neurodegeneration), Dr. Sid Kennedy (depression)
Imaging and medical devices: Dr. David Jaffray (radiation physicist and Director of STTARR), Dr. Narinder Paul (cardiothoracic imaging at TGH)

11. A centre for Global clinical trials
Toronto Region is the place for Global Clinical Trials
Informatics and Data Access
High Percentage of Foreign- Born Residents

12. A centre for Global clinical trials
Toronto Region is the place for Global Clinical Trials
Lower clinical trial management costs than in the U.S.
Improved approval speed and further cost reductions, thanks to a recent move to a single ethics review for multi- centre clinical trials
Data compiled from
For more information, contact Clinical Trials Ontario -

13. A centre for Global clinical trials
Informatics and Data Access
The Institute for Clinical Evaluative Sciences (ICES) leads cutting-edge studies that evaluate health care delivery and population outcomes and access a vast and secure array of Ontario’s demographic and health-related data, including
population-based health surveys
anonymous patient records
clinical and administrative databases
Robust digital infrastructure to support data collection and sharing
For more information, contact ICES -

14. A centre for Global clinical trials
High Percentage of Foreign-Born Residents
The Toronto region has a large, diverse population which provides a unique pool of potential participants.
Foreign-born population
Other
Source: Statistics Canada (Toronto & Montreal Census Metropolitan Areas) and US Census (US Metropolitan Statistical Areas)

15. Advanced business environment
Established Industry ecosystem
Lower Cost of Doing Business
Access to Generous Tax Incentive Program

16. Advanced business environment
Established Industry ecosystem
800+ companies, 38,000 employees
Successful startups
Infonaut
Figure 1
iamsick.ca
Newtopia
Damiva
MyPSW
Seamless MD
Profound Medical
Eve Medical
Arctic Dx
eSight
ChipCare
Interface Biologics
NP Screen
Xagenic
PlantForm
Encycle
Formation Biologics
Northern Biologics
Highland Therapeutics
Transition Therapeutics
Trillium Therapeutics
Consumer & Digital Health
Medical Devices
Therapeutics
Home-grown companies
Think Research
Point Click Care
Synaptive
Novadaq
Tribute Pharmaceuticals
Cipher Pharmaceuticals
Apotex
ACD/Labs
LifeLabs
Dalton Pharma
Alphora Research
TheraPure
Concordia Healthcare Corp
Cynapsus Therapeutics
Aptose Biosciences
Digital Health
Medical Devices
Specialty Pharma
Laboratory Services
Manufacturing

17. Advanced business environment Multinational companies
Established Industry ecosystem (cont’d)
50+ multinational pharmaceutical medical device and digital health companies have their Canadian headquarters in the Toronto region
Multinational companies
Sanofi Pasteur
Baxter
Astellas Pharma
AstraZeneca
Bayer
Janssen
Eli Lilly
Takeda
Boehringer Ingelheim
EMD Serono
GlaxoSmithKline
Hoffman LaRoche
Pfizer
Celgene
Amgen
Shoppers Drug Mart
Walmart
Loblaws
Pharmaceutical
Consumer Health
J&J Medical
Philips Healthcare
Seimens Health
BD Canada
GE Healthcare
Medtronic
McKesson
Teva
Telus Health
Cisco
IBM Health
Dell
Xerox
Samsung
Microsoft
Fujifilm
Medical Devices
Generic Pharmaceutical
Digital Health

18. Advanced business environment
Lower Cost of doing business
Source: Competitive Alternatives, KPMG’s Guide to International Business Location Costs Edition
Canada has a cost advantage compared to U.S. The 3 major U.S. health sciences clusters are above the U.S. baseline for costs of doing business (Boston, NY, SF)
Source: KPMG. Competitive Alternatives: 2014 Edition. Pp

19. Advanced business environment
Access to Generous Tax Incentive Program
The Scientific Research and Experimental Development Tax Incentive Program (SR&ED) provides investment tax credits to individuals or corporations that conduct research and development in Canada
35% of eligible expenses
Refundable on the first $3M of SR&ED expenses
Taxable income and taxable capital thresholds to be maintained for refund- ability
Provincial refund ability
20% of eligible expenses
40% refund ability on SR&ED expenses in excess of $3M
Other Benefits:
accelerated write-offs, timing on utilization of expenditures, unused credits carry forward
Provincial Credits also available
Source & more info at:

20. Dynamic Metro Region Large, fast growing North American metro region
You and Your Employees Will Love Living Here
High quality of life & lower cost of living
Connected to the world

21. Large, fast growing North American metro region
Dynamic Metro Region
Large, fast growing North American metro region
The region welcomes about 100,000 new residents every year. Canada’s skills-based immigration system ensures many are highly skilled
Big city opportunities for work & play
53%
13%
22%
27%
29%
Source: Statistics Canada (Toronto & Montreal Census Metropolitan Areas) and US Census (US Metropolitan Statistical Areas) for US Cities, 1991 for Canadian Cities

22. You and Your Employees Will Love Living Here
Dynamic Metro Region
You and Your Employees Will Love Living Here
#1 Best Place to Live Cities Ranking, January 2015
(Safety, liveability, cost of living, business environment, democracy and food security)
Source:

23. High Quality of Life – Lower cost of living
Dynamic Metro Region
High Quality of Life – Lower cost of living
Recruitment and retention of top talent advantage
Enjoy widespread opportunity of a big city without the sacrifices typically associated with big cities
City
Pricing Index
Normalized pricing of home purchase
Normalized pricing for appartment rental
Toronto
74.3
$2,680
$1,090
Montreal
81.8
$3,220
$1,360
New York
100
$11,060
$3,380
Los Angeles
75.8
$3,300
$1,200
Chicago 79
$3,170
$1,400
Source: Prices & Earning, CIO Wealth Management Research, Sept 2012

24. Toronto region is one flight away
Dynamic Metro Region
Toronto region is one flight away
Toronto is a global hub with 2 international airports connecting the Toronto region to the world.
Within a day’s trip of major U.S. centres like Boston, New York and Chicago
Dedicated downtown rail link

25. Come discover the action
Talent
Investors
Business
Be at the centre of over $1 billion in annual research spending, global calibre of basic and translational research, vibrant clinical research networks and a thriving independent clinical research community
Live big in a large, cosmopolitan and diverse mega-city with a quality of life friendly to families and young professionals
Tap into strong, geographically concentrated network of universities/colleges, 9 research hospitals, established companies and vibrant start-ups
Discover a target rich environment for a diverse health investment portfolio at attractive valuations
Assess centralized health data and large diverse pool of potential clinical trial patients, who are more motivated and educated than many other groups, including the U.S.
Take advantage of a lower cost business environment, generous tax incentives and government support

26. Want to learn more?
Contact us at:
tohealth.ca
@TOHealthToronto