1. An Overview of the Research Institute 2017
Professor Nicholas Forsyth
Director, Institute for Science & Technology in Medicine, Keele University

2. www.keele.ac.uk Keele University
A campus-based university located in the West Midlands of England, offering dual-honours degrees and research in science, social science and humanities.
Founded as a University College in 1949, it received its Royal Charter in 1962.

3. Guy Hilton Research Centre
Huxley Building and extension 2017
David Weatherall Bldg
McKay Building
Guy Hilton Research Centre

4. “translating basic science insights into medical application through provision of a multidisciplinary research environment”
ISTM brings together clinicians and bio-scientists across three hospital sites and the Keele campus:
University Hospital of North Midlands, Hartshill, Stoke-on-Trent
The Haywood Hospital, Burslem, Stoke-on-Trent
Robert Jones & Agnes Hunt Orthopaedic Hospital, Oswestry
School of Medicine
School of Pharmacy
School of Health & Rehabilitation
School of Life Sciences
ISTM Away Day 2016

5. Translational Research
“bench to bedside”
Industrial
Partnership
Industrial
Partnership
Potential
Clinical application
Clinical Trial
Basic science
Cell biology/ Physics/
Biological Chemistry
Bioengineering/
Imaging/
In vitro/ In vivo
modelling

6. ISTM - Current Staff
56 full members: - Professors: Readers: Senior Lecturers: Lecturers: Research Fellows: 5
Many affiliated members from other Keele RI’s
Key chair appointments of senior clinical/non clinical academics to expand capacity
Early Career Researchers recruited in Schools of Medicine, Pharmacy and SHAR

7. ISTM – Executive Committee
Director:
Prof Nicholas Forsyth
Director of Postgraduate Studies:
Prof Paul Horrocks
Theme leads:
Prof Alicia El Haj
Dr Alan Richardson
Dr Ed Chadwick

8. ISTM – Scientific themes
Regenerative Medicine
Healthcare Technologies
Therapeutics

9. Regenerative Medicine
Theme leader: Prof Alicia El Haj
Basic research into cell physiology and pathology, to developing new therapies in the laboratory, translating to treatments in the clinic and then assessing their efficacy by running clinical trials.
European Centre of Excellence in Tissue Engineering.
ARUK Centre of Excellence (+ Newcastle, Aberdeen, York)
EPSRC Doctoral Training Centre in Regenerative Medicine (+ Loughborough and Nottingham)
Part of 2 UK Regenerative Medicine Platform (UKRMP) hubs

10. Healthcare Technologies
Theme leader: Dr Ed Chadwick
Uses science and engineering principles to tackle the physical limitations brought on by neuromuscular and skeletal disease, injury and ageing:
Investigating biomechanical and physiological causes
Developing Assistive devices to restore function
Mathematical and conceptual models for biomedical and rehabilitation engineering research.

11. Therapeutics Theme leader: Dr Alan Richardson
Basic and translational research into human
disease that will ultimately lead to new therapies.
Neuroscience
Cancer
Nanotherapeutics
Medicines use plus: fertility, genetic epidemiology, drug delivery, platelets, malaria

12. Quality definitions

13. ISTM Income from HEFCE QR and Research Grants & Contracts 2011/12 to 2015/16
QR figures supplied by David Myatt: £1,709,352 forecast for 2015/16

14. ISTM – Postgraduate Training
PhD / Mphil / DM level research training, part- or full-time.
Masters courses: Biomedical Engineering Cell & Tissue Engineering Engineering Design
Growing cohort of overseas students, eg Iraq students.
Annual Symposium
PGR training activities
new PGR students at the Guy Hilton Research Centre 2016

15. ISTM – Training Researchers
Mentoring early-career lecturers and fellows
Research fellows transition to independence
Grant crafting and support panel
~35 research assistants and technical staff
Support and activities: eg Keele ACORN studentships, start-up funds incl. HEFCE Capital Equipment funds, workshops.

16. International links to ISTM
International links include China, Malaysia, India, Saudi Arabia, USA
International research facilities, eg French synchrotron
Researcher exchanges – eg ERASMUS
Funded international projects – eg MagNETicFUN, European Research Council Fellow (Prof Mel Mather)

17. ISTM - Enterprise Activities
Industrial collaborations, eg: - Innovation UK collaborative projects
MRC, BBSRC CASE and EPSRC CDT studentships, with UK companies
European joint projects involving Small & Medium Sized Enterprises
Collaborative and contract research with UK / worldwide companies, eg:
Athersys Inc (Cleveland, USA), Charnwood Molecular Ltd (Nottingham BioCity UK), Patara Pharma LLC (San Diego, USA), InterMune UK Ltd (Welwyn GC, UK), Glaxo SmithKline (London, UK), Lucideon Ltd (Stoke-on-Trent, UK), PneumaCare Ltd (Cambridge UK), Wolters Kluwer Health Ltd (Netherlands), XenoGesis Ltd (Nottingham BioCity UK).
Licensing of Intellectual Property
MRDC bid
Examples of current spin-off companies from ISTM:
NanoTherics ( Mica Biosystems (

18. Web pages and contacts:
PA to Director: Tracy Stanyer
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Director: Prof Nicholas Forsyth
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Business Operations Manager: Jeanette Forrester
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RI Manager: Mark Smith
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