1. (A) Right eye of a 28-month-old boy before topical cysteamine therapy, showing abundant crystals. (B) Same eye as in A after 7 months of 0.5 percent cysteamine eyedrops administered 8 to 12 times per day, with clearing of corneal crystals. (C) Left eye of 21-year-old woman prior to cysteamine eyedrop therapy. Uniform haziness typifies appearance of cornea at this age. (D) Same eye as in C after several months of diligent therapy with 0.5 percent cysteamine eyedrops. Cornea is clear to inspection, although crystals remain visible on slit-lamp examination. (Courtesy of Dr. MI Kaiser-Kupfer, National Eye Institute, National Institutes of Health, Bethesda, Maryland.)
Source: Cystinosis: A Disorder of Lysosomal Membrane Transport, The Online Metabolic and Molecular Bases of Inherited Disease
Citation: Valle D, Beaudet AL, Vogelstein B, Kinzler KW, Antonarakis SE, Ballabio A, Gibson K, Mitchell G. The Online Metabolic and Molecular Bases of Inherited Disease; 2014 Available at: Accessed: October 02, 2017
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