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The blood, lymphatic system & Immune system

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Presentation on theme: "The blood, lymphatic system & Immune system"— Presentation transcript:

1 The blood, lymphatic system & Immune system
Medical Terminology

2 Adenoid/o adenoids

3 Clumping/sticking together
agglutin/o Clumping/sticking together

4 Angi/o Vessel (blood vessel)

5 Arteri/o artery

6 cyt/o cell

7 erythr/o red

8 fung/o fungus

9 Hem/a, hem/o, hemat/o blood

10 Iatr/o Physician/treatment

11 Immun/o Immune; protection

12 Kary/o nucleus

13 Leuk/o white

14 Log/o study

15 Break down; dissolve; loosen
Ly/o Break down; dissolve; loosen

16 Lymph/o, lymphat/o lymph

17 Lymphaden/o Lymph node

18 Lymphangi/o Lymphatic vessel

19 morpho/o Shape; form

20 Bone marow; spinal cord
myel/o Bone marow; spinal cord

21 nucle/o nucleus

22 path/o disease

23 phag/o Eat; swallow; engulf

24 phleb/o vein

25 Ser/o serum

26 Splen/o spleen

27 Thromb/o clot

28 Thym/o thymus

29 Tonsill/o tonsils

30 Tox/o poison

31 Ven/o, Ven/i vein

32 Vir/o virus

33 Prefixes Prefix Meaning anti- against con- together; with macro- large
meta- change; beyond poly- many; much

34 Suffixes Suffix Meaning -blast developing cell -crit to separate -emic
pertaining to blood condition -phage eat; swallow -plasm formation; structure -poiesis formation

35 Fluid Systems of the Body
Blood: part of the circulatory or cardiovascular system Lymph: part of the lymphatic system; a clear fluid a. Contains white blood cells (WBCs) to help remove wastes, germs, toxins and other substances from tissues b. Controls fluid levels in tissues

36 Functions of the Blood A. Carry oxygen (O2) from lungs to the cells and remove wastes B. Remove carbon dioxide (CO2) to prevent waste buildup in the cells of your body C. Defends body against infection and disease

37 Structures of the blood
Blood Cells: Manufactured in the bone marrow Erythrocytes (red blood cells): carry O2 to body cells and remove wastes i. Contain hemoglobin which is a specialized protein used to carry O2 and CO2

38 Structures of the blood
b. Leukocytes (white blood cells): defend against infection and disease; two main types i. polymorphonuclear: WBCs that have a nucleus made up of several segments. Also called granulocytes because their cytosol is filled with granules.

39 Types of Polymorphonuclear WBCs
Neutrophils: Phagocytes; destroy harmful pathogens by engulfing them and breaking them down with enzymes. Eosinophils: secrete chemicals to attack disease causing parasites. Also respond during an allergic reaction by causing inflammation. Basophils: Contain histamine and heparin histamine: chemical that the body releases during an inflammatory response. Heparin: prevents coagulation or clotting

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42 Mononuclear WBCs ii. Mononuclear: WBC that only have one nucleus; also called agranulocytes because their cytosol does not have any granules. 1. lymphocytes: immune surveillance; detect and destroy foreign cells. 2. Monocytes: phagocytes that ingest and dispose of dead or dying cells a. Macrophages: monocytes that are found in tissues instead of bloodstream. Mostly found in the spleen, liver and connective tissue.

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44 Structures of the Blood
c. Thrombocytes (platelets): Aid in coagulation; cell fragments that have been broken off of megakaryocytes (bone marrow cells that have very large nuclei.)

45 Structures of the Blood
B. Plasma: liquid portion of the blood that contains water, hormones, proteins, sugar, salts, and wastes. Four key proteins found in plasma help the body function effectively.

46 Proteins in Plasma Albumin: water level maintenance in blood
Globulins: alpha and beta globulins transport lipids. Gamma globulins act as antibodies. Fibrinogen: key protein involved in blood clotting. Prothrombin: another protein involved in blood clotting.

47 Functions of the Lymphatic & Immune Systems
Protect the body from pathogens (bacteria, viruses, fungi, parasites, tpxins, allergens and cancer cells. Relies on organs from several body systems. Integumentary system: skin acts as a barrier from pathogens Respiratory system: cilia and mucous membranes help trap foreign particles Digestive system: the stomach produces acids and enzymes to destroy foreign invaders. Lymphatic system: plays a central role

48 Structures of the lymphatic system
Lymph/lymphatic fluid/interstitial fluid: colorless fluid that leaves the blood capillaries and circulates through a pathway of vessels and tissues. Lymphatic vessels: carry lymph to tissues of the body. a. Only move in one direction (towards the thoracic cavity) and contain valves to prevent backflow

49 Structures of the lymphatic system
C. Lymph nodes: Small bean-shaped structures that can filter foreign substances from lymph a. also produce lymphocytes which can detect and destroy pathogens.

50 Structures of the lymphatic system
D. Tonsils: Small mass of lymphatic tissue that form a protective ring in the pharynx; Three types. Can trap pathogens that enter through the throat and the nose. a. palatine tonsils: found on either side of the throat b. lingual tonsils: at the base of the tongue c. adenoids/pharyngeal tonsils: in the upper part of the throat (nasopharynx)

51 Structures of the lymphatic system
E. Thymus: gland located in the upper mediastinum (area of the chest between the lungs). Begins to atrophy after puberty. a. T lymphocytes produced in bone marrow mature in the thymus and then enter the bloodstream

52 Structures of the lymphatic system
F. Spleen: largest lymphatic organ a. Filters blood by destroying worn out erythrocytes b. produces lymphocytes c. stores thrombocytes d. reservoir for blood

53 Structures of the lymphatic system
G. Liver (found in RUQ): a. filters blood through hemolysis hem/o/lysis: b. storage for healthy erythrocytes erythr/o/cyt/es:

54 Structures of the lymphatic system
H. Peyer’s patches: small bundles of lymphatic tissue in the walls of the small intestines. a. protect against invaders that enter through the digestive system.

55 Structures of the Immune system
A. T cells: Different types of T cells are involved in immunity a. Cytotoxic cells (T8 cells): attach themselves to antigens and destroy those substances b. Helper cells (T4 cells): aid B cells in recognizing antigens and stimulating antibody (Ig) production

56 Structures of the Immune system
c. Natural Killer cells (NK cells): usually target cancer cells or viruses by recognizing the specific sugars they have on their surface d. Suppressor cells: slow or stop the activity of B or T cells once the foreign invader has been destroyed or controlled

57 Structures of the Immune system
B Cells: turn into plasma cells in response to an antigen and then secrete immunoglobulins (specific antibodies). This is referred to as humoral immunity. There are five classes of immunoglobulins: a. IgA: Found in respiratory and GI tracts. They are also secreted in saliva, tears, and breast milk. b. IgD: found in blood plasma in small amounts. Attach themselves to the surface of B cells to act as antigen receptors

58 Structures of the Immune system
c. IgE: secreted by plasma cells in skin, tonsils, and respiratory and GI tracts; stimulate histamines so useful in allergic responses d. IgG: Main defense against infection invaders. Can provide fetal immunity. e. IgM: help fight blood infections. Can bind to B-cells and act as powerful agglutinating agents.

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60 Types of Immunity Immunity is the ability to resist pathogens and toxins that cause infection and disease Natural Immunity: Immunity you were born with Your body is predisposed to protect you from certain diseases because of your race, gender, or species Feline leukemia Sickle cell anemia Prostate cancer vs. cervical cancer

61 Types of Immunity B. Acquired immunity: The body’s ability to protect itself against a specific bacterium, virus, etc. a. acquired active immunity: Body is exposed to and learns to defend against the pathogen i. immunity through a disease: after being invaded by a pathogen and surviving, B and T cells produce memory cells that can help prevent reinfection.

62 Types of Immunity ii. Immunity through a vaccine: person is injected with modified pathogen or toxin that will prime immune system to potential attacks from pathogens. b. Acquired passive immunity: short term immunity that comes from antibodies produced in a body other than your own. i. Serum from the blood of an animal or other person ii. Injections of gamma globulins from other people iii. Newborns getting antibodies from mother iv. Bone marrow transplant from a healthy person to a diseased individual. (Ex. Leukemia, severe anemia, etc.)

63 tonsils Cervical lymph node Right lymphatic duct Thymus gland Axillary lymph nodes spleen Thoracic duct Cistern chyli Peyer’s patches Lumbar lymph nodes Appendix Pelvic lymph nodes Inguinal lymph node Bone marrow

64 Arteriole Lymphatic capillary Endothelial cells Blood vessel capillaries Venule

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