1. Catalytic activation of carbon-carbon bonds in cyclopentanones
Y. Xia, G. Lu, P. Liu, Guangbin Dong, Nature, 2016,
University of Texas, Austin
Group Seminar
Author: Yann Baumgartner
Research Group: Prof. O. Baudoin

2. Previous Strategies for C-C Bond Cleavage
L. Souillart, N. Cramer, Chem. Rev., 2015, 115,

3. Previous Strategies for C-C Bond Cleavage
S-G. Lim, H. Lee, C-H. Jun, J. Am. Chem. Soc., 2001, 123, 751–752
M. Murakami, H. Amii, Y. Ito, Nature, 1994, 370,

4. This Work’s Strategy A. Masarwa et. al., Nature, 2014, 505, 199-203
Y. J. Park, J.-W. Park, C.-H. Jun, Acc. Chem. Res., 2008, 41,

5. Optimization of Reaction Conditions

6. Substrate Scope

7. Optimization of Reaction Conditions

8. Substrate Scope

9. Gram-scale Synthesis and Application

10. Preliminary Mechanistic Experiments

11. DFT-calculations

12. Thank You
For Your Attention