1. Liver Contrast Enhanced Ultrasound Perfusion Imaging in the Evaluation of Chronic Hepatitis C Fibrosis: Preliminary Results 
Antonio Orlacchio, Francesca Bolacchi, Maria Chiara Petrella, Daniela Pastorelli, Gabriele Bazzocchi, Mario Angelico, Giovanni Simonetti 
Ultrasound in Medicine and Biology 
Volume 37, Issue 1, Pages 1-6 (January 2011)
DOI: /j.ultrasmedbio
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

2. Fig. 1
Image shows ROI positioning over the right liver lobe (largest square) and over the portal vein (smallest square) in a 65-year-old woman with fibrosis score 2.
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

3. Fig. 2
(a–b) The time-acoustic intensity curves of 64-year-old woman with fibrosis score 1 (a) and a 70-year-old man with fibrosis score 3 (b). In the upper position is the PV curve, and in the lowest position the liver parenchyma curve. Echo mean is the mean echo intensity values in the selected ROI. Absolute time is the time course analysis.
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

4. Fig. 3
Correlation between PVPSI with fibrosis scores. Values are median, range and interquartile range (p = 0.19).
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

5. Fig. 4
Correlation between LPPSI with fibrosis scores. Values are median, range and interquartile range (∗p < 0.05).
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

6. Fig. 5
Correlation between δPSI (PVPSI − LPPSI) with fibrosis scores. Values are median, range and interquartile range (∗p < 0.05).
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

7. Fig. 6
(a–b) AUC-ROC graphs show diagnostic accuracy for severe fibrosis of LPPSI (a) and δPSI (b).
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions

8. Fig. 7
Graph shows comparison between LPPSI and δPSI ROC curves. No significant statistical difference was observed between the two curves (p = 0.82).
Ultrasound in Medicine and Biology  , 1-6DOI: ( /j.ultrasmedbio )
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology Terms and Conditions