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CELLULAR RESPIRATION Definition
Process of releasing energy (catabolism) stored in molecules to produce ATP which is used to drive biosynthetic reactions (anabolism).
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CELLULAR RESPIRATION Energy-Releasing Pathways
Anaerobic Definition Energy exchange occurring in the cell cytoplasm that does not use oxygen as the final electron acceptor. Aerobic Energy exchange occurring in the mitochondria using oxygen as the final electron acceptor.
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OXIDATION/REDUCTION Redox Coenzymes Hydrogen Atoms Oxidation
Reducing NAD+ and FAD Accept H atoms to become NADH & FADH2 Oxidizing NADH and FADH2 Release H atoms to become NAD+ & FAD Hydrogen Atoms Oxidation Release an electron to become H+
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ANAEROBIC CELLULAR RESPIRATION
Glycolysis Glucose ----> 2 Pyruvate + 2 ATP + 2 NADH
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Figure 8.4
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ANAEROBIC CELLULAR RESPIRATION
Alcoholic Fermentation Pyruvate ----> 2 Ethanol + CO2 + 2 ATP
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ANAEROBIC CELLULAR RESPIRATION
Lactate Fermentation Pyruvate ----> 2 Lactate + 2 ATP
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ANAEROBIC CELLULAR RESPIRATION
Anaerobic Electron Transport Sulfates & Nitrogen used as electron acceptors
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AEROBIC CELLULAR RESPIRATION
I. Pyruvate/Krebs Cycle Bridge Pyruvate ----> Acetyl CoA + CO2 + NADH
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AEROBIC CELLULAR RESPIRATION
II. Krebs (Citric Acid, TCA) Cycle Acetyl CoA + Oxalacetate ----> Citrate + CO2 + NADH + FADH2
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Fig. 7.2
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AEROBIC CELLULAR RESPIRATION
III. Electron Transport Chain NADH ----> NAD+ + H+ + e- FADH2 ----> FAD + 2H+ + 2e-
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AEROBIC CELLULAR RESPIRATION
IV. Chemiosmosis (Electron Transport Phosphorylation) ATP Synthase ADP + Pi > ATP (H+)
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AEROBIC CELLULAR RESPIRATION
V. Final Electron Acceptance H+ + e- + ½ O2 ----> H2O
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CELLULAR RESPIRATION Final Endproducts CO2 H2O ENERGY (100% Potential)
36 ATP or 38 ATP (40%) ANAEROBIC: 2 AEROBIC: (Skeletal Muscles & Brain) 36 (Liver, Kidneys, Heart) HEAT (60%) Unusable energy for the cell
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Fig. 7.9
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CARBOHYDRATE CELLULAR RESPIRATION
Glycogen ----> Glucose ----> Pyruvate Pyruvate Anaerobic (Possible Pathways) ----> Glycerol ----> Alcohol ----> Lactate ----> Amino Acids Aerobic (Possible Pathways) ----> Acetyl CoA ---> Krebs Cycle----> Chemiosmosis ----> Fatty Acids ----> Triglycerides
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PROTEIN CELLULAR RESPIRATION
Proteins ---> Amino Acids (AA) ----> Deamination (-NH3+) Amino Acids (Possible Pathways) a) Pyruvate ----> Glucose ----> Glycerol ----> Acetyl CoA b) Acetyl CoA ----> FA ---> TG ----> Krebs ---> ETP c) Oxalacetate ---> Krebs ---> ETP 2) NH > Ammonia ----> Urea
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LIPIDS CELLULAR RESPIRATION
Triglycerides--> Fatty Acids + Glycerol 1) Fatty Acids ----> Acetyl CoA ----> Krebs Cycle ----> Chemiosmosis 2) Glycerol----> Pyruvate ----> Glucose ----> Amino Acid ----> Acetyl CoA
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ALCOHOL CELLULAR RESPIRATION
Ethanol ---> Acetaldehyde ---> Acetyl CoA Acetyl CoA ----> Krebs Cycle ----> Chemiosmosis ----> Fatty Acids ----> Triglycerides
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