1. Drugs acting on Nervous system
Belladonna

2. Recap In the last class we learnt about The monograph of CNS drug
Hyoscyamus

3. Objectives On completion of this lesson,you would be able to
learn about
The monograph of CNS Drug
BELLADONNA

4. Atropa belladonna
Fig.30.1 Belladonna plant

5. BELLADONNA Syn: Deadly Nightshade Biological Source :
Dried or fresh leaves, flowering
and fruiting tops of
Atropa belladonna (European)
Atropa acuminata (Indian)
Family: Solanaceae
Geographical source :
South Europe, England,
Germany, U.S.A,
India (Simla, Kashmir,
Himachal Pradesh)
Fig.30.2

6. Cultivation, Collection And Preparation
Done at altitudes of about 1400m
Sowing is done in May & July
Seedlings are carefully transplanted
in September
Use of fertilizers like Urea, Potash & Super phosphate and insecticide spray increases yield
Fig.30.3

7. Cultivation, Collection And Preparation
Leaves and flowering tops are cut for at least 3 times a year at an interval of 2 months from 1-3 year old plants
When plants are 4 year old roots are dug out
PREPARATION:
Leaves are dried at C, if not dried properly deteriorate and give off ammonia o
Fig.30.4

8. Morphological Characters
LEAF:
Size: Length 5-25cm, Width cm
Shape: Ovate, lanceolate
Apex: Acuminate
Margin: Entire
Fig.30.5

9. Morphological Characters
LEAF:
Lamina : Decurrent
Colour : Green to brownish green
Odour : Slight and characteristic
Taste : Bitter and acrid
Extra feature : Most leaves are
transversely broken
Fig.30.6

10. Chemical Constituents
Contains Tropane alkaloids
L - Hyoscamine
Atropine
Belladonine
Scopoletin(l-methyl aesculetin)
Hyoscine
Pyridine
N-methyl Pyrroline
Volatile oil
Fig.30.7

11. Antispasmodic in case of intestinal gripping
Uses
Antispasmodic in case of intestinal gripping
Parasympatholytic with Anticholinergic activity
Reduce secretion of sweat, saliva and gastric juice
Mydriatic

12. Uses Antidote in Opium and Chloral hydrate poisoning
Tincture of Belladonna used as Sedatives
Digestive disorder, Diarrhoea and pancreatitis
In the treatment of Peptic Ulcer

13. Adulterants
Phytolacca americana
Solanum nigrum
Ailanthus glandulosa

14. Summary In this class we learnt about
The monograph of the CNS plant drug
BELLADONNA

15. Quiz Belladonna contains b) Quinoline alkaloids c) Pyrrole alkaloids
a) Indole alkaloids
b) Quinoline alkaloids
c) Pyrrole alkaloids
d) Tropane alkaloids

16. Quiz 2. Belladonna alkaloids are a) Cholinergic drugs
b) Anticholinergic drugs
c) Sympatholytic drugs
d) None of the above

17. Frequently Asked Questions
1. Write the macroscopy of Belladonna
Mention the chemical constituents of
Belladonna
3. Write the Botanical Source and Morphology of Belladonna
4. Write the uses of Belladonna