1. CatView Ltd Disposable View Catheter
Moshe Refael CEO

2. Contents The technology platform The product Development roadmap
Regulatory pathway
Investment sought.

3. Key Personal The Entrepreneurs: Moshe Refael – CEO
Prof. Steve Lipson. Optics, Technion Haifa
Prof. Ariel Roguin. MD, Rambam Hospital Haifa
Dr. Yaron Hefetz Optics, GE Haifa
Avinoam Baruch, Mech. Eng.

4. Current Endoscopy Methods
Regular metal pipe line guides
NO Viewing guides available on the market (not created.. yet)

5. The problem Part 1 There are 4 major problems:
Light scattering by blood cells.
Optical absorption by plasma
To provide an image using a few optical fibers.
To introduce a stent in the right position

6. The solution
The planned catheter guide To have a channel for introducing a clear liquid in front of the camera, in order to clear the red blood cells and improve the transparency

7. The solution
To provide a viewing guide which allows placement of the stent in the optimum position.

8. The angiographic beauty of stenting
The regular procedure
The angiographic beauty of stenting

9. Stent Placement
Guide
Balloon
Stent

10. CatView Product The Solution:
* To develop a guide with real-time visual observation capabilities, with or without a working channel.
* Following this, surgeons will be able to conduct their guides in real time as in gastroscopy.

11. The Technology Platform
The project will create a platform for minimal invasive treatment such as:
Heart Catheterized procedures
Anaesthetization.
Lungs – Bronchoscopy.
Urology – in-vivo observation and biopsy
Brain blood vessel inspection and treatment

12. CatView’s Catheter Features
Camera creating 80 pixel image Optical fiber bundle with 100 fibers, outer diameter 250µm, for illumination and imaging Nozzle to introduce a clear physiological fluid in front of the imaging lens Navigation drive Total 325± 25 µm diameter

13. The calculation is as follows:
Optic Calculation
Requirements
The calculation is as follows:
The required resolution according to the MD’s is 500µm
The cross-sectional area of the artery is: 4=15.5mm2
Image is projected onto 100 optical fibers
Four fibers used for illumination

14. Fluid injection
Annular space around the fiber optic to transport clear fluid to the imaging region
Pump to introduce the fluid

15. Product Overview The Diastolic Head The Intracorpus probe Proximate
Joystick
Light source
Liquid Pump
Proximate
Interface
USB Interface

16. Front end- Probe
Lens
Liquid spraying nozzles
Navigating head

17. Probe’s Cross\cut section
Fiber Optic Bundle
Vacuum & pressure
tubular + SPRED LIQUIDS

18. Cross Cut section 2

19. Navigator system

20. Probe’s cross section Fiber Optic bundle Vacuum liquid nozzle
Transparent liquid pipe
Fiber Optic bundle
Vacuum liquid nozzle

21. Proximate Unit Liquids pipe Optic fiber Lens Beam Splitter
Reflected Image
Light source
CMOS Camera
Camera Board

22. Activities Technological: Detailed design study. Management:
Breadboard system
Testing
Management:
Market search & Business Plan
Patent search & PCT filing.
Helsinki Approval
Marketing (for raising money)
Preliminary experiments on animals
Regulatory strategy
FDA path (Human experiments – 3rd year)
Technical writing

23. Gantt R &D Activities 2016 2017 2018 Characterizing Optical design
Mechanical design
Purchasing*
Building of first model
Lab test first round
Re-design after test
improvement
Business Plan
Strategic regulation
Helsinky certification
Animal trails
FDA approval
Human trails
Marketing**
Money In
500$ K
$1.5M
$ 4M
* Fibers, Camera board, Beam splitter, pump, Joystick
** marketing = Raising money

24. Thank you