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Volume 62, Issue 5, Pages (November 2002)

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1 Volume 62, Issue 5, Pages 1732-1742 (November 2002)
Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico- histopathological analysis of 96 patients  Herbert A. Hauer, Ingeborg M. Bajema, Hans C. Van Houwelingen, Franco Ferrario, Laure-Hélène Noël, Rüdiger Waldherr, David R.W. Jayne, Niels Rasmussen, Jan A. Bruijn, E. Christiaan Hagen  Kidney International  Volume 62, Issue 5, Pages (November 2002) DOI: /j x Copyright © 2002 International Society of Nephrology Terms and Conditions

2 Figure 1 Scatter plots with regression line for the percentage of cellular crescents versus baseline glomerular filtration rate (GFR0;A), GFR at 18 months (GFR18;B), and corrected GFR at 18 months (CORGFR18;C). In panel A, r = , P = 0.007; in B, r = 0.029, P = 0.796; in C, r = 0.301, P = Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

3 Figure 2 Scatter plots with regression line for the percentage of glomeruli with fibrinoid necrosis versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = , P = 0.281; in B, r =0.309, P = 0.005; in C, r = 0.464, P < Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

4 Figure 3 Scatter plots with regression line for the percentage of sclerotic glomeruli versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = , P = 0.003; in B, r = , P < 0.001; in C, r = , P = Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

5 Figure 4 Box plots for the severity of interstitial fibrosis versus GFR0 (A), GFR18 (B), and CORGFR18 (C). In panel A, r = , P < 0.001; in B, r = , P < 0.001; in C, r = , P = Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

6 Figure 5 Scatter plot with regression line for GFR0 versus GFR18 (r = 0.673,P < 0.001). Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

7 Figure 6 Scatter plot of the estimated GFR18 versus the measured GFR18 (r2 = 0.602, SD = mL/min). The estimated GFR18 was calculated by the following formula: Estimated GFR18 (mL/min) = × GFR0 (mL/min) × fibrinoid necrosis (%) × segmental crescents (%). Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions


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