1. Early Philadelphia Neurology
HISTORY OF Neurology
Early Philadelphia Neurology
Charles Mills, MD & Francis Xavier Dercum, MD
Richard J. Barohn, MD
The University of Kansas Medical Center

2. Charles Karsner Mills, MD 1845-1931
Born in Philadelphia
Served as a soldier in the Civil War
Univ. of Penn:
1869 – Medical School
1871 – PHD
Initially practiced General Medicine
Practiced devoted to nervous & mental diseases throughout Philadelphia
Established Neuro Ward in 1887 at Philadelphia General Hospital
“Old Blockley”
Lecturer of Electrotherapeutics at Univ of Penn
Charles Karsner Mills, MD

3. Charles Karsner Mills, MD (1845-1931)
Professor of Nervous & Mental Diseases, Philadelphia Polyclinic –
Clinical Professor of Nervous Diseases at Univ of Penn –
Professor of Neurology at Univ of Penn – 1903
President of ANA – 1886 & 1924
Founder of Philadelphia Neurologic Society
Founder of Philadelphia Post Graduate School of Neurology

4. Charles Karsner Mills MD 1845-1931
Textbook: The Nervous System and It’s Diseases (1898)
He compared it to Gowers book!
Dedicated to Weir Mitchell
Emphasis of methods of neurological exam and localization
Chapter on chemistry of nervous system
Aphasia and localization papers – 1904 & 1915
Alcoholic neuropathy and psychic phenomena
A case of unilateral progressive ascending paralysis, probably representing a new form of degenerative disease
J Nerv Ment Dis 1900;27:
Called “Mills Syndrome”: variant of ALS
Descending Paralysis – 1906
Occlusion of the superior cerebellar artery – 1912
250 journal articles

6. The Nervous System and Its Diseases
Charles Mills, MD; 1898

7. J Nerv Ment Dis 1900;27:
JAMA. 1906;XLVII(20):

8. Francis Xavier Dercum, MD 1858-1920
Born in Philadelphia
U of Penn Med School 1877, PhD 1878
Private practice & also demonstrator at U Penn in histology /physiology
Published on sensory organs, semicircular canals 1878/9
Prof of Nervous Disease Jefferson Med College in 1872
Chair of Nervous Disease, U Penn in 1884
Philadelphia General Hospital staff
President of ANA in 1896
Late in life focused on psychiatry & endocrinology

9. Francis Xavier Dercum, MD 1858-1920
A Textbook on Nervous Diseases by American Authors st multi-authored neuro-text with only American Authors
F.X. Dercum – Phil (6 chapters)
General Considerations
Neuorasthenia
Arrested Development, Malformations
Diseases of the Membranes, Sinuses , and Brain Tissue
Cererbal Palsies of Childhood
Paretic Dementia
S Weir Mitchell- Phili Infirmary Nerv Dis (1)
William Osler –Balt, Johns Hopkins (1)
Diseases the Direct or Indirect result of Infection
Charles Dana - NY, Bellevue Hosp (1)
Hemorrhage, Embolism, and Thrombosis
M. Allen Starr-NY Columbia (1)
Tumors
W.W. Keen- Phil, Infirmary Nerv Dis (1)
Surgery of the Brain, Spinal cord, and nerves
Charles Mills- Phil Phil Hosp (1)
The Anatomy of the Cerebral Cortex and the Localization of its Function
Frederick Peterson- NY, Columbia (3)
Bulbar Palsy
Multiple Cerebro-Spinal Sclerosis

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