1. By dr.safeyya alchalabi
Psychotropic drugs
By dr.safeyya alchalabi

2. Psychotropic drugs Mood stabilizers Anxiolytic (antipsychotic)
depressants
Anxiolytic
Neuroleptics
(antipsychotic)
Mood stabilizers

4. Antidepressants Monoamine oxidize Inhibitors MAOIs
Tricyclic Antidepressant
TCAs
Selective Serotonin Reuptake Inhibitors
SSRIs
Selective Norepinephrine Reuptake Inhibitors
SNRIs
Dual Action Antidepressants
Atypical antidepressant
Mood Stabilizers

8. orthostatic hypotension
TCA
antihistaminic
sedation
weight gain
anticholinergic
dry mouth
dry eyes
constipation
memory deficits
urinary retention
antiadrenergic
orthostatic hypotension
sexual dysfunction
cardiotoxicity
QT lengthening
Side effect

9. orthostatic hypotension
MAOI
orthostatic hypotension
weight gain
dry mouth
sedation
sexual dysfunction
sleep disturbance
Hypertensive crisis
Serotonin Syndrome
Side effect

11. SSRI Side effect GI upset anxiety restlessness insomnia fatigue
sexual dysfunction
anxiety
restlessness
nervousness
insomnia
fatigue
dizziness
discontinuation syndrome

12. SSRI Fluoxetine Sertraline Paroxetine Paxil Fluvoxamine Citalopram
Prozac
Fluoxetine
Zoloft
Sertraline
Paxil
Paroxetine
Luvo
Fluvoxamine
Celexa
Citalopram
Lexapro
Escitalopram

14. Mood Stabilizers Indications Classes Lithium, anticonvulsants,
Bipolar
cyclothymia
schizoaffective
impulse control
intermittent explosive disorders
Lithium,
anticonvulsants,
antipsychotics
Classes

15. lithium Only medication to reduce suicide rate.
Rate of completed suicide in BAD ~15%
Effective in long-term prophylaxis of both mania and depressive episodes in 70+% of BAD I pts
Factors predicting positive response to lithium
Prior long-term response or family member with good response
Classic pure mania
Mania is followed by depression

16. lithium baseline creatinine, TSH CBC In women check a pregnancy test
Before starting get
baseline creatinine,
TSH
CBC
In women check a pregnancy test

17. lithium Steady state achieved after 5 days-
Monitoring:
Steady state achieved after 5 days-
check 12 hours after last dose, once stable check 3 months
TSH and creatinine 6 months.

18. Lithium side effects
Most common are GI distress including reduced appetite, nausea/vomiting, diarrhea
Thyroid abnormalities
Non significant leukocytosis
Polyuria/polydypsia secondary to ADH antagonism. In a small number of patients can cause interstitial renal fibrosis.
Hair loss, acne
Reduces seizure threshold, cognitive slowing, intention tremor

19. Lithium toxicity
Mild- levels see vomiting, diarrhea, ataxia, dizziness, slurred speech, nystagmus.
Moderate nausea, vomiting, anorexia, blurred vision, clonic limb movements, convulsions, delirium, syncope
Severe- >2.5 generalized convulsions, oliguria and renal failure