1. SWAG SSG Skin Meeting Thursday 22nd September 2016 Maxine Taylor
Clinical Research Network
West of England
SWAG SSG Skin Meeting
Thursday 22nd September 2016
Maxine Taylor
Senior Research Delivery Manager – Cancer, Surgery, Genetics, Haematology.
Workforce Development Lead

2. Clinical Research Network & Cancer Services
West ofEngland
SWAG - Somerset Wiltsire Avon & Gloucestershire
South West Children’s Cancer & Leukaemia
Research Network

3. 30 Clinical Specialties Ageing Anaesthetics & pain Cancer
Cardiovascular
Children
Critical Care
Dementia & Neurodegenerative
Dermatology
Diabetes
ENT
Gastroenterology
Genetics
Haematology
Health Services
Hepatology
Infectious Diseases
Injuries & Emergencies
Mental Health
Metabolic & Endocrine
Musculoskeletal
Neurological
Opthalmology
Oral & Dental
Primary Care
Public Health
Renal
Reproductive Health
Respiratory
Stroke
Surgery

4. NIHR CRN High Level Objectives
Increase number of participants into NIHR CRN portfolio studies
650,000 in England
21,905 in West of England
Increase the number of studies that deliver to time and target
Target 80%
Increase number of commercial studies delivered through network
650 new studies this year
75% of all commercial studies
Reduce NHS study set up times
Reduce time taken to recruit first participant

5. NIHR CRN Objectives for cancer
Recruit 20% of cancer incidence
West of England 1,909
Recruit 7.5% of cancer incidence into interventional studies
716
Include challenging studies
Cancer surgery – 4 recruits per 100,000 population
Radiotherapy – 6 recruits per 100,000 population
Rare cancers (<6 per 100,000) – 12 recruits per 100,000 population
Children & young people – 3 per 100,000 population
Teenagers & young adults – record number of year olds participating in research

6. Including lymphoma

7. National Clinical Studies Groups PPI Psychosocial & Survivorship
Imaging Adv. panel
Breast Cancer
CSG
Brain Tumours
CSG
Lung Cancer
CSG
Palliative & Supportive
Care
Head & Neck
CSG
Biomarkers Adv. panel
Upper GI Cancer
CSG
Consumer Liaison Group
Sarcoma
CSG
PPI
Colorectal Cancer
CSG
Melanoma
CSG
Kidney Cancer
CSG
Primary
Care
Lymphoma
CSG
Bladder Cancer
CSG
Screening, Prevention & Early Diagnosis
Haematol.
CSG
Testis Cancer
CSG
Prostate Cancer
CSG
Gynae Cancer
CSG
Children’s Cancer & Leukaemia
Teenage &
Young Adult
CTRad (Radiotherapy)

8. 2016-17 to date Cancer recruitment per LCRN

9. to date
West of England recruitment to Cancer studies per Trust

13. Studies in setup Currently no studies in setup
Open studies per Trust
Project Title
Chief Investigator
Site parent organisation
Principal Investigator
BRAG rating
Project site planned recruitment end date
Recruited (total)
Project site target participants
EORTC Adjuvant Pegylated Interferon in Ulcerated Melanoma
Gloucestershire Hospitals NHS Foundation Trust
Farrugia, Dr David
30/11/2017 8
An Open-Label, Phase 1, Dose Escalation Study of MLN2480 in Patients with Relapsed or Refractory Solid Tumors Followed by a Dose Expansion Phase in Patients With Unresectable Melanoma.
Middleton, Prof Mark
University Hospitals Bristol NHS Foundation Trust
Herbert, Dr Chris
01/08/2016 4 5
Studies in setup Currently no studies in setup
BRAG
Open studies
Black
Study not reported recruitment or study has not recruited
Red
% Recruitment is more than 30 behind % time elapsed, i.e. Difference < -30
Amber
% Recruitment is less than 30 behind % elapsed time but more than 0 behind % elapsed time, i.e. -30 < Difference < 0
Green
% Recruitment is equal to or greater than % elapsed time, i.e. Difference >= 0
Grey
Unable to calculate RAG due to record missing at least one data point

14. Useful links https://www.crn.nihr.ac.uk/
National and local network information including training programmes templates, tools, contacts, videos etc
Open data platform. Look at performance across whole CRN including all specialty areas
/csg.ncri.org.uk/portfolio/portfolio-maps/
View current national portfolio of open, closed and ‘in set up’ studies
See where a study in open across the country
Search for a study to fit criteria. Good for horizon scanning, eligibility criteria

15. Contacts Research Delivery Manager – maxine.taylor@nihr.ac.uk
Cancer portfolio facilitator –