1. Beaumont Hospital Breast Service
Breast Cancer Family Risk Assessment Guidelines
Low Risk
Medium Risk
High Risk
One 1st degree relative with breast cancer > 40 years.
One 2nd degree relative at any age.
One 1st degree relative with breast cancer < 40 years.
Two 1st or 2nd degree relative with breast cancer at an average age of >50 years.
Three 1st or 2nd degree relatives with breast cancer at an average age of >60 years.
Two 1st or 2nd degree relative with breast cancer at an average age of < 50 years (One must be 1st degree relative).
Three 1st or 2nd degree relatives with breast cancer <60 years (one must be 1st degree relative).
Four relatives with breast cancer at any age (one must be a 1st degree relative).
Ovarian Cancer
One relative with ovarian cancer at any age PLUS on the same side of the family there is:
One 1st degree relative with breast cancer before age of 50.
One additional relative with ovarian cancer at any age.
Two 1st or 2nd degree relatives with breast cancer at an average age of <60.
Bilateral Breast Cancer
One 1st degree relative with cancer in both breasts before average age of 50.
One 1st or 2nd degree relative with bilateral breast cancer AND one 1st or 2nd degree relative with breast cancer <60 years.
Male Breast Cancer
One male breast cancer at any age PLUS ON SAME SIDE OF FAMILY:
One 1st or 2nd degree relative with breast cancer before 50.
Two 1st or 2nd degree relatives with breast cancer before average age of 60.
Imaging Required
Base line mammogram if over 35years old.
No further imaging required until National Breast Screening Programme at 50 years old
Imaging Required
Baseline mammogram if over 35 years old
Annual Mammography for women aged between 40-49, (G.P. to arrange same).
Women aged over 50 years, mammography in the National Breast Screening Programme.
IBIS Risk Assessment
Lifetime risk of breast cancer is less than 17%.
Less than 3% risk of developing breast cancer in the next 10 years for women aged
Follow up
Discharge to primary care
IBIS Risk Assessment
Lifetime risk of breast cancer is greater than 17% but less than 30%.
A 3%-8% risk of developing breast cancer in the next 10 years for women aged
Significant Factors
Bilateral Breast Cancer
Male Breast Cancer
Ovarian Cancer
Jewish Ancestry
Sarcoma in a relative <45
Glioma or childhood adrenal cortical carcinomas
Complicated patterns of multiple cancers at a young age.
Follow up
Discharge to primary care
Mammography unit will facilitate annual mammography as requested by primary care physician
Imaging Required
IBIS score >30% Annual MRI from 30 years old & Annual mammography from 40 years old.
IBIS score <30% Annual mammography from 35 years.
(Review need for MRI at 50years old).
IBIS Risk Assessment
Lifetime risk of breast cancer is 30% or greater.
Risk of faulty gene: BRCA1, BRCA2 or TP53 gene is 20% or greater.
A greater than 8% risk of developing breast cancer in next 10 years for women aged 40-49
1st Degree Relative
Mother
Father
Daughter
Son
Sister
Brother
2nd Degree Relative
Grandparent
Grandchild
Aunt
Uncle
Niece
Nephew
Half Sister
Half Brother
3rd Degree Relative
Great-grandparent
Great-grandchild
Great Aunt
Great Uncle
Cousin
Follow up
Annual outpatient review with clinical examination and imaging results
Reviewed 10/11/15