1. TCRN F2F Meeting 2016

2. Roswell Park Cancer Institute
Located in Buffalo, New York
27 acre main campus and five affiliated sites
Independent, free standing cancer institute since 1898
NCI designated comprehensive cancer center since 1974
133 hospital beds
3,282 employees
309 faculty members and over 100 senior scientists
20 scientific shared resources

3. Roswell Park Cancer Institute
5,284 hospital admissions, 224,000 outpatient visits, 31,000 patients under active care/year
Cancer Registry Cases In 2015:
4,067 ( analytic class 00-22)
480 (non-analytic class 32: 1st course treatment elsewhere, subsequent treatment at RPCI)
2,160 (non-analytic class 30-43, including consults, e.g., path)
Service/Referral Areas
Primary catchment area: 8 county regions of Western New York, 1.5 M (86%) of RPCI patients
48 states
13 foreign countries

4. Current RPCI TIES Statistics
Loaded path reports
Time span: 1995 to 09/2016
Patients: 90,203
Reports: 195,174
38,372 reports, /2016, recently loaded, being QCed
Live HL7 feed every six months beyond 9/2016
Registered users: 26

5. IT Tasks Completed since last F2F
Loaded surgical pathology reports from 1/1/2014 to 9/15/2016
Upgraded to TIES v 5.6.2
Performed validation of 2002 to 2016 cases uploaded into TIES against Tamtron
Missing reports were re-exported to be included in TIES
IT support, development, and maintenance 

6. Next IT Tasks
Run RPCI PHI checker scripts on newly loaded reports (1/1/2014 and 9/15/2016)
QC /2016 pathology reports
Review and revise errors in reports, e.g., MRNs format and missing names
Website update
Support evaluation and validation of new De-ID tool
Implement LDAP with TIES
Support upcoming development for CR data import into TIES

7. Quality Control User Audit – 6 months intervals Query Audit – annually
July 2016 audit – no issues to report
Query Audit – annually
Dec 2015 audit – no issues to report

8. Progress TIES has been live as 09/09/2015
26 active user accounts (14 in 2015)
4 fellows currently use TIES for research projects
TIES/TCRN Dissemination
Presentation and Demo
Disease Site Research Groups (10)
CCSG Scientific Programs (5)
Fellows
Website, fliers, Mission Magazine article
Pilot Projects

9. Pilot Projects
Skin ulceration in breast cancer staging (Dr. Thaer Khoury)
RPCI & UPitt
Manuscript accepted for publication Oct 2016, Breast Journal: “The Role of Skin Ulceration in Breast Carcinoma Staging and Outcome” TBJ R1
Intramammary LN, (Dr. Thaer Khoury)
Research in progress
RPCI, UPitt, UPen, AU

10. Supported External Projects
Demographic characterization of tenosynovial giant cell tumor, AU
Gene expression in endometriosis and endometriosis associated ovarian cancer, UPitt
Margin evaluation in early carcinomas of the oral tongue, UPitt
Skin cancer in post transplant patients, UPitt

11. RPCI Investigators/TIES User Questions/Interest
What other clinical data is accessible?
Would you have molecular results?
Could you also search radiology reports? (Clinical staging)
Can you search other centers data without IRB approval?
Could RPCI investigators search radiology reports loaded in other TIES nodes?
Awareness and level of interest is significantly growing

12. RPCI-TIES/TCRN Team and Roles
Dr. Carmelo Gaudioso, RPCI CoI., Executive TCRN Committee member
Monica Lopez Murphy, TIES Regulatory Administrator and TCRN P & P subcommittee member
Kelly Jans, TIES Regulatory Administrator, user educator
Mayur Sakthivel, TIES IT Administrator, responsible for RPCI TIES IT development

13. Q&A
Thanks!
Questions-Comments?