1. Bioinformatics Overview
Bioinformatics is the application of information technology to the management of biological data.
Bioinformaticians understand biological problems and computational solutions to produce useful tools.

2. Bioinformatics Outline
Molecular Biology
Data Searches
Substitution Patterns
Phylogenetics
Genomics
Protein and DNA Structure Prediction
Proteomics

3. Bioinformatics Outline
Perl
Bioinformatics tools

4. Molecular Biology Genetic material Gene structure Protein structure
Molecular biology tools
Genomic information

5. Data Searches Dot plots Alignments Scoring matrices
Dynamic programming
Global and local alignments
Multiple sequence alignments
Database searches

6. Substitution Patterns
Patterns of substitutions with Genes
Substitution numbers
Variations in Evolutionary rates
Molecular clocks

7. Phylogenetics Molecular phylogenetics Phylogenetic trees
Distance matrix methods
Maximum likelihood approaches
Multiple sequence alignments

8. Phylogenetics Parsimony Inferred ancestral sequences Faster searches
Consensus trees
Tree confidence
Molecular phylogenies

9. Genomics Prokaryotic genomes Prokaryotic gene structure GC content
Prokaryotic gene density

10. Genomics Eukaryotic gene structure Open reading frames GC content
Gene expression
Transposition
Eukaryotic gene density

11. Protein and DNA Structure Prediction
Amino acids
Polypeptide composition
Secondary structure
Tertiary and quaternary structure
Modeling protein folding
Structure prediction

12. Proteomics Protein classification Experimental techniques
Inhibitors and drug design
Empirical methods
NMR structure
Post-translational modification prediction

13. Perl for Bioinformatics
Getting started with Perl
Sequences and strings
Mutation and randomization
Genetic code

14. Bioinformatics Tools
equence analysis, pairwise alignment, and database searching
Multiple sequence alignments
Visualizing pattern structures
Prediction protein structure and function from sequence
Genomics and proteomics