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Polymyositis Associated With Severe Interstitial Lung Disease

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Presentation on theme: "Polymyositis Associated With Severe Interstitial Lung Disease"— Presentation transcript:

1 Polymyositis Associated With Severe Interstitial Lung Disease
Bakewell Catherine J. , MD, Raghu Ganesh , MD  CHEST  Volume 139, Issue 2, Pages (February 2011) DOI: /chest Copyright © 2011 The American College of Chest Physicians Terms and Conditions

2 Figure 1 Postero-anterior chest radiograph at initial presentation demonstrating irregular streaky opacities consistent with interstitial fibrosis at the lung bases bilaterally. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

3 Figure 2 A, Initial high-resolution CT (HRCT) scan of the chest demonstrating interstitial pneumonia with ground glass opacification, mild intralobular septal thickening, and subtle honeycombing, with subpleural sparing consistent with features of nonspecific interstitial pneumonia. B, HRCT scan 20 months later demonstrates complete resolution of previously noted changes. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions

4 Figure 3 Histopathologic examination of transbronchial lung biopsy specimen. A, Plugs of granulation tissue characteristic of organizing pneumonia. A mechanically crushed inflammatory infiltrate is also present (hematoxylin and eosin stain, original magnification × 10). B, Mostly compressed alveolar lung tissue with mild lymphocytic inflammation in the top of the image (hematoxylin and eosin stain, original magnification × 20). Together the images show cellular (lymphocytic) interstitial pneumonitis with organizing pneumonia. CHEST  , DOI: ( /chest ) Copyright © 2011 The American College of Chest Physicians Terms and Conditions


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