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& Laurence S. Sperling, M.D., FACC

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1 & Laurence S. Sperling, M.D., FACC
Diabetes & CV Care Roundtable Session 3: Harmonizing Care Adapting the “Heart Team” Approach June 20, 2017 Robert H. Eckel, M.D., FAHA & Laurence S. Sperling, M.D., FACC

2 About the Presenters DISCLOSURES
Laurence S. Sperling, MD, FACC Professor of Medicine Director of The Center for Heart Disease Prevention Emory University School of Medicine Atlanta, GA DISCLOSURES No potential conflicts related to this presentation

3 About the Presenters DISCLOSURES
Robert H. Eckel, M.D. Professor of Medicine Division of Endocrinology, Metabolism and Diabetes Division of Cardiology Professor of Physiology and Biophysics Charles A. Boettcher II Chair in Atherosclerosis University of Colorado Denver Anschutz Medical Campus Director Lipid Clinic, University of Colorado Hospital DISCLOSURES No conflicts related to this presentation

4 Partnership / Coordinated Care Critical
Chronic disease states Recognition of negative consequences of fragmented care Examples HIV Breast Cancer Solid Organ & Bone Marrow transplantation Endocrine Surgery

5 “Heart Team” Concept Adapt to a comprehensive diabetes care team
Central to TAVR , Multiple vessel CAD (Class 1 Rec both European & ACC / AHA GLs) Advanced heart failure , Adult congenital Adapt to a comprehensive diabetes care team

6 Vital Importance of Involvement by an Informed Patient
Choices regarding diagnostic and therapeutic options should be made through a process of shared decision-making involving the patient and provider, explaining information about risks, benefits, and costs to the patient. I IIa IIb III

7 The Heart Valve Team and Heart Valve Centers of Excellence
Recommendations COR LOE Patients with severe VHD should be evaluated by a multidisciplinary Heart Valve Team when intervention is considered I C Consultation with or referral to a Heart Valve Center of Excellence is reasonable when discussing treatment options for 1) asymptomatic patients with severe VHD, 2) patients who may benefit from valve repair versus valve replacement, or 3) patients with multiple comorbidities for whom valve intervention is considered IIa

8 Heart Team Approaches to Revascularization Decisions
A Heart Team approach to revascularization is recommended in patients with unprotected left main or complex CAD. Calculation of the STS and SYNTAX scores is reasonable in patients with unprotected left main and complex CAD. I IIa IIb III I IIa IIb III B

9 BARI 2D Trial: Primary Endpoint
5-year death rate difference did not reach statistical significance. Death (%) n =155 n =161 BARI 2D Study Group, NEJM 2009

10 Risk Factor Goals Smoking Status: No smoking* LDL-C: <100 mg/dL*
Non-HDL-C: <130 mg/dL* TG: <150 mg/dL** SBP: <130 mmHg* DBP: <80 mmHg* Hemoglobin A1C: <7%* *Goals based on Smith S et al. AHA/ACC Secondary Prevention Guidelines 2006 Update. JACC 2006;47:2130-9

11 Additional studies are needed to define optimal target levels for systolic BP and A1C for patients with T2DM.

12 Treating the ABCs Reduces Diabetic Complications
Strategy Complication Reduction of Complication Blood glucose control Heart attack CVD 37%1 10%2 Blood pressure control Cardiovascular disease Heart failure Stroke Diabetes-related deaths 51%3 56% 4 44% 4 32% 4 Lipid control Coronary heart disease mortality Major coronary heart disease event Any atherosclerotic event Cerebrovascular disease event 35% 5 55%6 37%6 53%5 1 UKPDS Study Group (UKPDS 33). Lancet. 1998;352: 2 Kelly TN et al, Ann Int Med 2009: 3 Hansson L, et al. Lancet. 1998;351: 4 UKPDS Study Group (UKPDS 38). BMJ. 1998;317: 5 Grover SA, et al. Circulation. 2000;102: 6 Pyŏrälä K, et al. Diabetes Care. 1997;20:

13 Suboptimal CVD Risk Factor Control in T2DM
2018 adults, years old without CVD, 43% male, 55% African Americans - MESA, ARIC, Jackson Heart Study 42% HbA1c <7% 41% BP <130/80 mmHg 27% LDL-C <100 mg/dl 7.2% at goal for HbA1c, BP, and LDL-C  risk of CVD with # of risk factors controlled 1 – 36% 2 – 52% 3 – 62% Wong ND et al. Diabetes Care, 39: , 2016

14 “Heart Team”- Key Elements
Patient is center of the heart team Shared decision making Core is multidisciplinary coordinated care Focus on: Integrated practice unit Improved quality/ outcomes Systems approaches Holmes D, et al Eur Heart J 2014;35(2):66-68 Head SJ, et al Eur Heart J 2013;

15 Diabetes Comprehensive Care Team (DCCT)
Minimal “Start team? Optimal care team? Infrastructure Alignment of incentives/goals Need to change reimbursement model and what is “valued”

16 The Minimal “Heart Team”
Preventive cardiologist Diabetologist Certified Diabetes Educator Nurse Practitioner, RN and/or RD

17 The Optimal “Heart Team”
Preventive cardiologist(s) Diabetologist(s) Certified Diabetes Educator Nurse Practitioner, RN and/or RD Pharm D Ready access to consultants Nephrology Retinology Podiatry Vascular medicine Non-Invasive Imaging Cardiology and/or radiology

18 Cardiometabolic Health Alliance / Diabetes Collaborative Registry
American College of Cardiology American Association of Clinical Endocrinology National Minority Quality Forum Association of Black Cardiologists


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