1. Traumatic Brain Injury and Mitochondrial Dysfunction
John B. Hiebert, MD, Qiuhua Shen, PhD, APRN, Amanda R. Thimmesch, BA, Janet D. Pierce, PhD 
The American Journal of the Medical Sciences 
Volume 350, Issue 2, Pages (August 2015)
DOI: /MAJ
Copyright © 2015 Southern Society for Clinical Investigation Terms and Conditions

2. Figure 1
An illustration superoxide to the hydroxyl radical leading to cellular damage. Included are the 2 antioxidants, glutathione and catalase.
The American Journal of the Medical Sciences  , DOI: ( /MAJ )
Copyright © 2015 Southern Society for Clinical Investigation Terms and Conditions

3. Figure 2
An imbalance between reactive oxygen species (ROS) and antioxidants when traumatic brain injury (TBI) occurs. This is called oxidative stress.
The American Journal of the Medical Sciences  , DOI: ( /MAJ )
Copyright © 2015 Southern Society for Clinical Investigation Terms and Conditions

4. Figure 3
Traumatic brain injury (TBI) affects the mitochondrial neuron and damages the supercomplexes within the electron transport chain.
The American Journal of the Medical Sciences  , DOI: ( /MAJ )
Copyright © 2015 Southern Society for Clinical Investigation Terms and Conditions

5. Figure 4
The pathophysiologic sequence of traumatic brain injury (TBI) damaging the electron transport chain resulting in reactive oxygen species and subsequent apoptosis and necrosis.
The American Journal of the Medical Sciences  , DOI: ( /MAJ )
Copyright © 2015 Southern Society for Clinical Investigation Terms and Conditions