Download presentation
Presentation is loading. Please wait.
Published byMelissa Carr Modified over 6 years ago
1
Discriminatory and predictive capabilities of enzyme-linked immunosorbent assay and multiplex platforms in a longitudinal Alzheimer’s disease study Wesley Jongbloed, Maartje I. Kester, Wiesje M. van der Flier, Robert Veerhuis, Philip Scheltens, Marinus A. Blankenstein, Charlotte E. Teunissen Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 9, Issue 3, Pages (May 2013) DOI: /j.jalz Copyright © 2013 The Alzheimer's Association Terms and Conditions
2
Fig. 1 Bland–Altman plots of ELISA and xMAP data. Bland–Altman plots for Aβ42, Tau, and pTau depicting the effect of average biomarker concentrations (x-axis) on the ratio between ELISA and xMAP values (y-axis). A concentration-dependent effect is observed for all three biomarkers. ∗∗P < .01. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2013 9, DOI: ( /j.jalz ) Copyright © 2013 The Alzheimer's Association Terms and Conditions
3
Fig. 2 Kaplan–Meier curves for each biomarker measured in ELISA and xMAP. Kaplan–Meier curves for Aβ42, Tau, and pTau for the conversion to Alzheimer’s disease within the group of mild cognitive impairment patients. Time (years) represents the time between the first lumbar puncture and follow-up diagnosis. Aβ42 levels below and Tau and pTau levels above the median are considered Alzheimer’s disease positive. Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2013 9, DOI: ( /j.jalz ) Copyright © 2013 The Alzheimer's Association Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.