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Figure 1 Food, nutrition, obesity, physical activity, and the cellular processes linked to cancer
Figure 1 | Food, nutrition, obesity, physical activity, and the cellular processes linked to cancer6. Nutritional factors can influence cancer development by affecting fundamental cellular processes, including those that regulate the balance between cell proliferation and death, appropriate cell differentiation, the expression of oncogenes and tumour-suppressor genes, cell signalling, and other factors in the cellular environment (such as hormonal factors) that influence gene expression. Thus, bioactive food components can interact with gene expression at multiple points, and furthermore, a specific food typically contains numerous components that interact additively or even synergistically with these cellular processes. Permission obtained from World Cancer Research Fund International © World Cancer Research Fund/American Institute for Cancer Research Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective (AICR, Washington District of Columbia, USA, 2007). Permission obtained from World Cancer Research Fund International © World Cancer Research Fund/American Institute for Cancer Research Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective (AICR, Washington District of Columbia, USA, 2007) Mayne, S. T. et al. (2006) Diet, nutrition, and cancer: past, present and future Nat. Rev. Clin. Oncol. doi: /nrclinonc
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